Objective: Use of the search filter ‘exp animals/ not humans.sh’ is a well-established method in evidence synthesis to exclude non-human studies. However, the shift to automated indexing of Medline records has raised concerns about the use of subject ...
Nicole Askin, Tyler Ostapyk, Carla Epp
doaj +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
A survey of Compliance of Persian Abstracts of Research Articles in Medical Journals of Universities of Medical Sciences (Type 1) with the Vancouver Guideline and ISO 214 Standard [PDF]
Background & Aims: An abstract is the best source of information within a content. The structured abstract is the best representation of the main source. Writing an appropriate abstract requires adherence to standards of abstracting.
Nasrin Makani +2 more
doaj
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Using sentiment analysis to identify similarities and differences in research topics and medical subject headings (MeSH terms) between Medicine (Baltimore) and the Journal of the Formosan Medical Association (JFMA) in 2020: A bibliometric study. [PDF]
Lin JK, Chien TW, Yeh YT, Ho SY, Chou W.
europepmc +1 more source
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
The Primary Care Electronic Library: RSS feeds using SNOMED-CT indexing for dynamic content delivery
Background Rich Site Summary (RSS) feeds are a method for disseminating and syndicating the contents of a website using extensible mark-up language (XML).
Judas Robinson +5 more
doaj +1 more source
The use of forest plot to identify article similarity and differences in characteristics between journals using medical subject headings terms: A protocol for bibliometric study. [PDF]
Yan YH, Chien TW.
europepmc +1 more source
MEDICAL SUBJECT HEADINGS IN MEDLARS.
Use of an identical subject heading list for both machine searching and publication creates problems. Necessary compromises include precoordination of some headings for publication and use of some coordinates in the computer system that are not appropriate for a printed index.
openaire +1 more source

