Results 81 to 90 of about 216,572 (291)

Improving PubMed Search Using Medical subject heading ( MeSH) Terms

Global Journal of Medical Therapeutics, 2023
Medical Subject Headings (MeSH) terms are valuable tools to conduct focused and concise search. This review article evaluates the performance of search strategies for retrieval of information from the national Library of Medicine (NLM) by using the Medical Subject Headings (MeSH) while searching for articles about analgesics used for pain management in
Mahvish Umar, Sadaf Sharif, Sana Younas
openaire   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Variations and trends in major research topics across leading general medical journals, 1966–2022

Critical Public Health
Attention to publication diversity calls for broader topic inclusion by journals. Although general medical journals have distinct editorial policies, cross-journal differences remain underexplored.
Nin-Chieh Hsu, Chia-Hao Hsu, Charles Liao, Yasuharu Tokuda   +3 more
doaj   +1 more source

Structuration sémantique des documents XML : Expérimentations et évaluation [PDF]

, 2014
National audienceLa norme XML permet la représentation d'un document selon un découpage logique qui ne reflète généralement pas la sémantique de son contenu. Il serait donc intéressant de compléter la structure logique des documents XML par une structure
Ben Meftah, Salma, Feki, Jamel, Khrouf, Kaïs, Soulé-Dupuy , Chantal   +3 more
core   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Automatic Category Recognition of MeSH Terms through Comparison of their Occurrence Frequency in Relevant and non-Relevant Documents

مدیریت اطلاعات سلامت, 2015
INTRODUCTION: Due to dynamic of terms, their classification is challenging. The current research aims at determining the usability of a model for automatic recognition of MeSH terms categories through measuring their occurrence frequency within relevant ...
Mohammad Tavakolizadeh-Ravari, Saeed Ghaffari, Forough Mostafavi   +2 more
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Gaps within the Biomedical Literature: Initial Characterization and Assessment of Strategies for Discovery

Frontiers in Research Metrics and Analytics, 2017
Within well-established fields of biomedical science, we identify “gaps,” topical areas of investigation that might be expected to occur but are missing. We define a field by carrying out a topical PubMed query and analyze Medical Subject Headings (MeSH)
Yufang Peng, Gary Bonifield, Neil R. Smalheiser   +2 more
doaj   +1 more source