Results 61 to 70 of about 1,460,022 (262)

Construction and evaluation of a chronic arthritis animal model induced by persistent activation of toll‐like receptors via lipopolysaccharide stimulation

Animal Models and Experimental Medicine, EarlyView.
We constructed a novel systemic juvenile idiopathic arthritis mouse model (LC) by introducing sustained TLR4 activation into the collagen‐induced arthritis model. The LC model effectively recapitulates human sJIA‐like systemic inflammation while revealing a critical dissociation between systemic immune activation and joint damage.
Fengming Li, Qiang Luo, Xinglin Wu, Yuxiao Chen, Xuemei Tang   +4 more
wiley   +1 more source

Which difficulties do GPs experience in consultations with patients with unexplained symptoms: a qualitative study

BMC Family Practice, 2019
Background Many general practitioners (GPs) struggle with the communication with patients with medically unexplained symptoms (MUS). This study aims to identify GPs’ difficulties in communication during MUS consultations.
Juul Houwen, Peter L. B. J. Lucassen, Anna Verwiel, Hugo W. Stappers, Willem J. J. Assendelft, Tim C. olde Hartman, Sandra van Dulmen   +6 more
doaj   +1 more source

Persistent pain: not a medically unexplained symptom [PDF]

British Journal of General Practice, 2011
At the same time as the study of pain is flourishing as a basic and applied science, and attention is paid nationally to reducing the gap between provision and need (chronic/persistent pain is a Royal College of General Practitioners priority for 2011-2013),1,2 there are moves to categorise it as a medically unexplained symptom (MUS).
Amanda C de C, Williams, Martin, Johnson
openaire   +2 more sources

Functional Problems: Prevalence In Secondary Care And Perceptions Of Doctors [PDF]

, 2012
1 Abstract 1.1 Title Functional problems: prevalence in secondary care and perceptions of doctors 1.2 Aims (a) To evaluate the prevalence of functional problems in general medicine, gastroenterology, gynaecology and psychiatry outpatient specialist ...
RAJAPAKSE, HARSHINI, Rajapakse, Harshini Iyanthimala   +1 more
core  

Medically unexplained physical symptoms

, 2008
Medically unexplained physical symptoms (MUPS) are physical symptoms which trigger the sufferer to seek healthcare, but which remain unexplained after appropriate medical assessment.
Price, Jonathan, Price, JR
core   +1 more source

Reframing the Gut–Brain Axis: The Gut Wall as a Neural Immune Interface in Multiple Sclerosis and Autoimmune Neurological Diseases

Annals of Neurology, EarlyView.
Gut wall physiology in multiple sclerosis (MS) and autoimmune neurologic diseases remains underexplored but may span gut barrier dysfunction, enteric glial targeting, mucosal immune dysregulation, and autoimmune targets within the enteric nervous system (ENS).
Federico Montini, Sean J. Pittock, Laura Cacciaguerra, Howard L. Weiner, Luke A. Schwerdtfeger   +4 more
wiley   +1 more source

Persistent bilateral breast pain treated with traditional Kampo medicine

Journal of General and Family Medicine, 2021
A 45‐year‐old woman presented with persistent bilateral breast and axillary pain lasting for more than 3 months. Lengthy work‐up failed to identify the etiology. Physical examination was entirely normal, including breast examination.
Kentaro Iwata, Takashi Nishimoto
doaj   +1 more source

Medically unexplained physical symptoms

, 2012
Medically unexplained physical symptoms (MUPS) are physical symptoms that trigger the sufferer to seek healthcare, but which remain unexplained after appropriate medical assessment.
Price, Jonathan, Price, JR
core   +1 more source

Duck Orbivirus and Egg Production: A Newly Identified Duck Orbivirus Is the Etiological Agent of Egg Production Decline in Chinese Breeder Ducks

Animal Research and One Health, EarlyView.
Field samples from breeder duck farms with egg‐production decline were subjected to viral detection, genome sequencing, and virus isolation. Experimental infection demonstrated that duck orbivirus (DORV) causes a significant and persistent reduction in egg production in breeder ducks.
Bing Li, Jianhua Wang, Xuezhi Cui, Xinxing Chu, You Wang, Dongmin Hao, Mingqing Xu, Haixia Chang, Huihui Li, Mingtian Mao, Mian Wu, Chengguang Lu, Jing Tang, Suyun Liang, Zhanbao Guo, Zhengkui Zhou, Youxiang Diao, Shuisheng Hou, Yi Tang   +18 more
wiley   +1 more source

The American College of Rheumatology Updated Recommended Methods for Development of Disease Classification and Response Criteria

Arthritis &Rheumatology, EarlyView.
Disease classification criteria and response criteria are important tools in the conduct of observational studies and clinical trials for rheumatic diseases. This paper updates methodologic guidance for classification and response criteria funded, developed and/or endorsed by the American College of Rheumatology (ACR), incorporating contemporary ...
Sindhu R. Johnson, Tuhina Neogi, Amy S. Turner, Jaime Guzman, Zahi Touma   +4 more
wiley   +1 more source