Results 21 to 30 of about 139,702 (165)

Cost-effectiveness analysis of Belimumab in patients with systemic lupus erythematosus in Spain [PDF]

Farmacia Hospitalaria, 2015
Objective: To estimate the cost-effectiveness of belimumab in patients with systemic lupus erythematosus (SLE) presenting positive biomarkers and active disease despite standard treatment (ST), from the Spanish social perspective.
Silvia Díaz-Cerezo, Ángel María García-Aparicio, Javier Parrondo, Laura Amanda Vallejo-Aparicio   +3 more
doaj   +1 more source

Parches transdérmicos anticonceptivos: evaluación de tecnología sanitaria

Revista Argentina de Salud Pública, 2023
INTRODUCCIÓN: La anticoncepción es un derecho, y es obligación del Estado garantizar el acceso a métodos anticonceptivos efectivos, seguros y de calidad.
Santiago Hasdeu, Guadalupe Montero, Florencia Albornoz, Daiana Campo, Daniela Villafañe, Gabriela Luchetti   +5 more
doaj  

Purification of Advanced Therapeutics by Flow‐Through Pseudo‐Affinity Chromatography: Bi‐Specific mABs, Fc Fusion Proteins, and Adeno‐Associated Viruses

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Modern biopharmaceutical manufacturing requires purification platforms capable of processing structurally and functionally diverse products while addressing the challenge of removing persistent and high‐risk host cell proteins (HCPs).
Wenning Chu, Eduardo Barbieri, Arianna Minzoni, Shriarjun Shastry, Jacob P. LeBarre, Qingbo Shu, Taufika Williams, Xuanwen Li, Divya Chandra, Xuankuo Xu, Jerome Bill, David Roush, Joseph Taris, Patrick Gilbert, Andre Kiesewetter, Oliver Rammo, Michael Schulte, Christopher Major, Trina Mouchahoir, Steven Cramer, Cristiana Boi, Ruben G. Carbonell, Abraham Lenhoff, Stefano Menegatti   +23 more
wiley   +1 more source

Process Analytical Technology (PAT) for Continuous Purification of mRNA via Precipitation and Tangential Flow Filtration

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Continuous downstream processing of messenger ribonucleic acid (mRNA) therapeutics requires purification strategies that are scalable, robust, and capable of removing product‐ and process‐related impurities from in vitro transcription mixtures.
Rajan R. Bhawnani, Maria del Carme Pons Royo, Rohan Kadambi, Andrew Hatas, Steve Burcat, Tyler Arnold, Hasan Al‐Mahayni, Richard D. Braatz, Allan S. Myerson   +8 more
wiley   +1 more source

Eco‐Efficient in Mediterranean Olive Grove Systems: Insights From a Life Cycle Cost Analysis in Southern Portugal

Business Strategy and the Environment, EarlyView.
ABSTRACT This study assesses and compares the eco‐efficiency of six olive production systems in the Alentejo region, southern Portugal, employing a life cycle costing (LCC) approach directly integrated with a prior life cycle assessment (LCA). Although LCC has been increasingly applied to Mediterranean olive‐growing, empirical research in Portugal ...
Rachel Hermeto de Pádua Souza, Rui Fragoso, Carlos Marques, Anna Irene De Luca   +3 more
wiley   +1 more source

Purification and concentration of model viruses using single‐pass tangential flow filtration

Biotechnology Progress, EarlyView.
Single‐pass TFF was developed for an enveloped and non‐enveloped virus for use in continuous downstream purification processes. Enveloped virus was concentrated and purified. Abstract The vaccine and viral vector industry is growing at an accelerated rate.
Luis Alberto Mejía‐Manzano, Lynn Manchester, Grace Wallis, Kan Wang, Bruce P. Lee, Michael Betenbaugh, Caryn L. Heldt   +6 more
wiley   +1 more source

Viscosity of concentrated mRNA solutions: Implications for downstream processing

Biotechnology Progress, EarlyView.
Abstract Messenger RNA (mRNA) therapeutics can be used to protect against infectious disease and for the treatment of cancers and genetic disorders. In order to obtain the desired therapeutic dosage, it is necessary to concentrate the mRNA to levels where the viscosity of the mRNA solutions can become significant.
Amin Javidanbardan, Fatemeh Najafi, Ziqiao Wang, Andrew L. Zydney   +3 more
wiley   +1 more source

Fármacos e alimentos: interações e influências na terapêutica [PDF]

Infarma: Pharmaceutical Sciences, 2014
Interações entre fármacos e alimentos podem ser determinantes na obtenção do sucesso terapêutico, devido a interferências tanto no metabolismo de fármacos quanto na absorção de nutrientes.
Márcia LOMBARDO, Jaqueline Kalleian ESERIAN   +1 more
doaj   +1 more source

Clinical Significance of Acute Kidney Injury in Idiosyncratic Drug‐Induced Liver Injury: A Multicentric Propensity Scores Matched Study

Clinical Pharmacology &Therapeutics, EarlyView.
Clinical significance of acute kidney injury in idiosyncratic drug‐induced liver injury: a multicentric propensity scores matched study. Evidence about the role of acute kidney injury (AKI) in idiosyncratic drug‐induced liver injury (DILI) is still scarce.
José María Pinazo‐Bandera, Hao Niu, Juan Pedro Toro‐Ortiz, Inmaculada Medina‐Caliz, Judith Sanabria‐Cabrera, Aída Ortega‐Alonso, Mercedes Robles‐Díaz, Daniel Enrique Di Zeo‐Sanchez, Nelia Hernández, Fernando Bessone, Vinicius Nunes, Raymundo Paraná, M. Isabel Lucena, Raul J. Andrade, Ismael Alvarez‐Alvarez, Miren García‐Cortés   +15 more
wiley   +1 more source

Bol CIM 248: Miopatías asociadas a medicamentos [PDF]

, 2020
Fil: Centro de Información de Medicamentos (CIM). Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas.
Centro de Información de Medicamentos - FCByF - UNR
core   +1 more source