Results 51 to 60 of about 1,267,063 (264)

An [Imperfect] Case for Dyadic Research in Pediatric Psychosocial Oncology

open access: yes
Pediatric Blood &Cancer, EarlyView.
Stephanie M. Nanos   +2 more
wiley   +1 more source

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo   +5 more
wiley   +1 more source

Epithelial-mesenchymal transition in cancer metastasis: Molecular mechanisms, microenvironmental regulation, and therapeutic targeting

open access: yesPrecision Medication
Epithelial-mesenchymal transition is a crucial driver of cancer metastasis, enabling cancer cells to acquire invasive and migratory characteristics. This review synthesizes the molecular mechanisms underlying EMT, focusing on the transcription factors ...
Yinuo Liu   +7 more
doaj   +1 more source

Health Literacy, Self‐Efficacy and Knowledge of Sickle Cell Disease Among Caregivers

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a hereditary blood disorder in which abnormal haemoglobin leads to severe anaemia, painful crises and organ failure. Caregivers’ health literacy (HL) – their ability to assess, understand and apply information, and interact with healthcare professionals – is crucial for managing children with SCD, yet ...
Melanie Bruinooge   +6 more
wiley   +1 more source

Reverse MIC drift of nemonoxacin and its advantages against Gram-positive bacteria: A 10-year multicenter surveillance study

open access: yesPrecision Medication
Background: Antimicrobial resistance (AMR) threatens global health. Conventional fluoroquinolones have experienced accelerated resistance due to target‑enzyme mutations and are further constrained by safety concerns.
Jie Wu, Yun Li, Bo Zheng
doaj   +1 more source

Leukemia and Exposure to Potential Benzene Sources in Children From the Mexico City Metropolitan Area, 2010–2021: A Geospatial Analysis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Leukemia is the most common childhood cancer in Mexico, and acute lymphoblastic leukemia (ALL) is the most frequent subtype. Exposure to high concentrations of benzene has been associated with ALL incidence, particularly in urban areas. This study evaluated the relationship between distance to benzene emission sources and the number
Orlando Rivera Zurita   +5 more
wiley   +1 more source

Medication adherence perspectives in haemodialysis patients: a qualitative study

open access: yesBMC Nephrology, 2017
Background End-stage kidney disease patients undergoing haemodialysis are prescribed with multiple complex regimens and are predisposed to high risk of medication nonadherence.
Saurav Ghimire   +3 more
doaj   +1 more source

Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte   +5 more
wiley   +1 more source

From medicine cabinets to ecosystems: a Europe-wide assessment of household pharmaceutical waste disposal practices

open access: yesFrontiers in Pharmacology
BackgroundUnused and expired household medicines contribute to environmental pollution, avoidable healthcare costs, and public health risks, including antimicrobial resistance. Although regulatory frameworks for pharmaceutical waste disposal exist across
Przemyslaw Kardas   +2 more
doaj   +1 more source

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