Results 111 to 120 of about 514,516 (351)

Evaluation of medication errors in one of the largest public hospital: A retrospective study

open access: yesClinical Epidemiology and Global Health
Background: In hospitals, medication errors still occur, especially in developing countries such as Indonesia. However, most incidents can be prevented.
Dewi Susanti Atmaja   +4 more
doaj   +1 more source

Are We Making Smart Pumps Smarter? [PDF]

open access: yes, 2018
Background: Medication errors comprise a significant proportion of medical errors, and are abundant, costly, and associated with causing harm to patients via adverse drug events. The most serious medication errors often involve IV medications.
Schaefer, Brittany
core   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Investigation of the Frequency and Types of Errors During the Preparation and Injection of Chemotherapy Drugs

open access: yesNovelty in Biomedicine
Background: Medical errors are common in the world, but in some wards and some conditions, they need a higher level of concern. Chemotherapy and its related wards are one of the concerning issues. There are limited studies about the occurrence of medical
Mahmoud Dehghani Ghorbi   +5 more
doaj   +1 more source

Medical Errors [PDF]

open access: yes, 2011
Overview: Time of Death: 5:07 p.m. – Proceeding the solemn afternoon of February 22nd 2003, the Santillian family listened on as doctors told them that their cherished loved one was officially pronounced brain dead and would soon have to be taken off ...
Spall, Jennifer
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

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