Results 141 to 150 of about 266,853 (264)

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Disparities in medication error reporting: a focus on patients with select protected characteristics. [PDF]

BMJ Open Qual
Bassi S, Jakubiel Smith O, Onatade R.
europepmc   +1 more source

Priorities in the Prevention Strategies for Medication Error Using the Analytical Hierarchy Process Method. [PDF]

Healthcare (Basel), 2022
Kim S, Kim H, Suh HS.
europepmc   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Asenapine-induced severe dystonia in a patient with schizophrenia: medication error due to sound-alike drug. [PDF]

BMJ Case Rep
Wulff S, Nielsen J, Pedersen N, Nielsen MØ.   +3 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

The impact of collaborative pharmaceutical care on hospital discharge medication error prevalence: A stepped-wedge cluster randomised trial. [PDF]

Explor Res Clin Soc Pharm
Kirwan G, Allen A, Deasy E, Delaney T, Hayde J, McManamly C, Wall C, O'Byrne J, Grimes T.   +8 more
europepmc   +1 more source

Exploring Nurses' Perceptions of Medication Error Risk Factors: Findings From a Sequential Qualitative Study. [PDF]

Glob Qual Nurs Res, 2022
Savva G, Papastavrou E, Charalambous A, Vryonides S, Merkouris A.   +4 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Exploring multidimensional determinants of medication error reporting in China: a qualitative study using the theoretical domains framework. [PDF]

Front Pharmacol
Guo H, Guo Q, Wang X, Liu Y, Wang Z.
europepmc   +1 more source