Results 41 to 50 of about 492,299 (347)

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

FEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász, Albert Bálint Papp, Lukács Sándor Lesinszki, Attila Mócsai, Tamás Varga, László Nagy, Péter Gogolák   +6 more
wiley   +1 more source

Medication administration error and contributing factors among pediatric inpatient in public hospitals of Tigray, northern Ethiopia

BMC Pediatrics, 2018
Background Medication administration error is a medication error that occurs while administering a medication to a patient. A variety of factors make pediatrics more susceptible to medication errors and its consequences.
Zeray Baraki, Mebrahtu Abay, Lidiya Tsegay, Hadgu Gerensea, Awoke Kebede, Hafte Teklay   +5 more
doaj   +1 more source

Medication errors and associated factors as perceived by nurses working at the national referral hospital in Bhutan

Bhutan Health Journal, 2022
Introduction: A common patient safety issue is medication error and this has remained a serious problem in hospital settings. Medication error occurs at any point of medication process: prescription, transcription, dispensing, and administration ...
Tshering Dema, Kencho Zangmo, Pema Dorji, Tshering Zangmo, Kezang Namgay, Kencho Wangdi, Sonam Jamtsho   +6 more
doaj   +1 more source

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

FEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki, Masae Ohtsuka, Takeshi Nakano, Masaru Tanokura, Takuya Miyakawa   +4 more
wiley   +1 more source

Identifying the Factors Affecting the Incidence of Medication Errors of Nurses in Teaching Hospitals of Shiraz University of Medical Sciences

Rāhburdhā-yi Mudīriyyat dar Niẓām-i Salāmat, 2021
Background: Medication errors are one of the major causes of injury to patients while receiving medical care. This study aimed  to investigate the effective causes of medication errors in nurses in educational hospitals affiliated with Shiraz University ...
Ali Reza Yusefi, Parnian Nikmanesh, Zahra Kavosi, Ahmad Sadeghi   +3 more
doaj  

Proportion of medication error reporting and associated factors among nurses: a cross sectional study

BMC Nursing, 2018
Background A medication error (ME) is any preventable event that may cause or lead to inappropriate medication use or patient harm. Voluntary reporting has a principal role in appreciating the extent and impact of medication errors.
Abebaw Jember, Mignote Hailu, Anteneh Messele, Tesfaye Demeke, Mohammed Hassen   +4 more
doaj   +1 more source

ACSS2 involved in acetyl‐CoA synthesis regulates skeletal muscle function

FEBS Letters, EarlyView.
The enzyme acyl‐coenzyme A synthetase short‐chain family member‐2 (ACSS2) catalyzes the conversion of acetate to acetyl‐CoA, but its function in skeletal muscle is unclear. We studied ACSS2 deficiency in mouse and fly models. Skeletal muscle from the mouse model showed atrophic fibers, excess lipid, and depleted NADH.
Mekala Gunasekaran, Gloriana Campos, Natalya M. Wells, Khanhlinh Lambuu, Isabelle Draper, Christina A. Pacak, Peter B. Kang   +6 more
wiley   +1 more source

Analisis Medication Error di Instalasi Farmasi Rawat Jalan RSPAD Gatot Soebroto Jakarta Pusat

Jurnal Manajemen dan Pelayanan Farmasi, 2023
Medication errors (MEs) have an impact on drug service inaccuracies and endanger patients at risk through a variable number of accidents, so it is necessary to conduct different methods and definitions study.
Ayyoehan Tiara Annisa, Nanang Munif Yasin, Susi Ari Kristina   +2 more
doaj   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source

Vertical gaze palsy due to medication error

Epilepsy and Behavior Case Reports, 2017
We present a teenage boy with recent onset of seizures, who was erroneously treated with a large dose of an antiseizure medication as a result of drug mix-up.
Shishir Rao, Meghan Harper-Shankie, Rajkumar Agarwal   +2 more
doaj   +1 more source