Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Usability and feasibility of consumer-facing technology to reduce unsafe medication use by older adults [PDF]
, 2019 Background Mobile health technology can improve medication safety for older adults, for instance, by educating patients about the risks associated with anticholinergic medication use.
Abebe, Ephrem +7 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Analysis of medication consultation networks and reporting medication errors: a mixed methods study
BMC Health Services Research, 2018 Background To examine characteristics of verbal consultation about medication within social networks of hospital inpatient medication system, and their associations with medication error reporting.
Pattarida Janmano +2 more
doaj +1 more source
Redesign Pelayanan Farmasi dengan Metode Failure Mode And Effect Analysis [PDF]
, 2011 Background: Pharmacy service is a high risk area in thesupport of health service quality. PKU Muhammadiyah Hospitalis a hospital that respons to systematic movement in servicesthat focus on patient safety such as minimizing the incidenceof medication ...
Supriyanti, E. (Eri)
core
Addendum to Informatics for Health 2017: Advancing both science and practice [PDF]
, 2017 This article presents presentation and poster abstracts that were mistakenly omitted from the original ...
Cornet, Ronald +3 more
core +4 more sources
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Factors Associated with the Incidence of Medication Errors and Nurses' Refusal to Error Reporting [PDF]
, 2016 Introduction:Medication errors may occur at every stage of the medicines prescription and distribution processes and as nurses can give more than 150 medicines to patients in one work shift, they are in the first line of medical errors.
Badiee, +6 more
core
What constitutes a high quality discharge summary?:A comparison between the views of secondary and primary care doctors [PDF]
, 2014 This study aimed to identify any differences in opinion between UK hospital junior doctors and community General Practitioners (GPs) with respect to the ideal content and characteristics of discharge summaries, and to explore junior doctors' training for
Bhattacharya, Debi +3 more
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source