Results 51 to 60 of about 2,808,658 (271)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Dose error reduction software in medication safety risk management – optimising the smart infusion pump dosing limits in neonatal intensive care unit prior to implementation

BMC Pediatrics, 2022
Background Smart infusion pumps with dose error reduction software can be used to prevent harmful medication errors. The aim of this study was to develop a method for defining and assessing optimal dosing limits in a neonatal intensive care unit’s smart ...
Sini Kuitunen, Krista Kärkkäinen, Carita Linden-Lahti, Lotta Schepel, Anna-Riia Holmström   +4 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Medication Administration Error Reporting Among Nurses: A Descriptive Qualitative Study [PDF]

Global Journal on Quality and Safety in Healthcare
Introduction Nurses are integral to the healthcare delivery team (multidisciplinary team). They are involved and play vital roles with responsibilities to ensure the quality of healthcare for their patients.
Dzidefo Tuvor, Augustine Kumah, Rebecca Abiti, Stephen Henry Afakorzi, Peter K. Agbemade, Christine Ahiale, Mac Dzodzodzi, Anthony Bless Dogbedo, Adanu Peter Worlasi, Emmanuel Obot, Janet Mawunyo Tornyi, Abdul-Razak Issah, Innocent Dzubey, Deborah Terkperkie Kanamitie   +13 more
doaj   +1 more source

GAMBARAN SIKAP PERAWAT DALAM MELAPORKAN INSIDEN MEDICATION ERROR [DESCRIPTION OF NURSES’ ATTITUDE IN REPORTING INCIDENTS OF MEDICATION ERROR] [PDF]

, 2021
Incident medication error reporting is a system of documenting incident medication error in the hospital to determine the cause of the incident for improvement and learning to prevent the same incident in the future.
Ompusunggu, Fransiska, Juniarta, Juniarta, Elvretta, Jesica Jane, Lase, Jultuti Arni, Sakerebau, Yuhelmita   +4 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Applying hierarchical task analysis to medication administration errors [PDF]

, 2006
Medication use in hospitals is a complex process and is dependent on the successful interaction of health professionals functioning within different disciplines.
Stanton, Neville A., Stanton, NA, Lane, Rhonda, Harrison, David, Harrison, DJ, Lane, R   +5 more
core   +1 more source