Results 151 to 160 of about 9,886,225 (302)

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Improving Medication Management in Indonesian Aged Care Homes: Research Priority Setting With Stakeholders. [PDF]

Pharmacol Res Perspect
Sari YM, Bell JS, Adhi S, Alhamid U, Dewiasty E, Dhanira A, Kusharto CM, Novriany ED, Notario D, Pambudi I, Situmeang R, Soenarti S, Widodo MR, Wangge G.   +13 more
europepmc   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Enablers and Barriers to Medication Self-Management in Patients With Type 2 Diabetes: A Qualitative Study Using the COM-B Model [PDF]

Huiqin Li,1 Ying Li,2,* Jing Wang,3,* Yuyao Zhang,1 Shiyan Ben1 1School of Nursing, Anhui University of Chinese Medicine, Hefei, People’s Republic of China; 2Clinical Pharmacy, The First Affiliated Hospital of Anhui University of Chinese Medicine,
Li H, Li Y, Zhang Y, Wang J, Ben S
core  

Is Ultra-Long-Term Subscalp EEG Ready to Go "Solo"? Transforming the Landscape of Antiseizure Medication Management. [PDF]

Epilepsy Curr
Feyissa AM.
europepmc   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

Molecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani, Laura Mariën, Caro De Weerdt, Sanne Wouters, Laure‐Anne Teuwen, Hans Prenen, Katleen Janssens, Timon Vandamme   +7 more
wiley   +1 more source

Medication Management Strategies at Hospital Admission: A Systematic Review and Meta-Analysis. [PDF]

Clin Transl Sci
Emadi T, Yiu CH, Liu S, Tang D, Yeung K, Baysari M, Budgeon C, Carter S, Criddle D, Fleming C, Francis M, Grover C, Hawthorne A, Hawthorne D, Khlentzos A, Khlentzos J, Krogh L, McMillan F, Moles R, Nguyen K, Oldfield L, Packer A, Penm M, Pham L, Phillips K, Poon S, Ratnanayagam G, Rigby D, Sanfilippo F, Shakib S, Tan E, Van Dort B, Yates P, Yik J, Angley M, Elliott RA, Penm J.   +36 more
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Understanding medication management in older adults: experiences of Turkish community pharmacists. [PDF]

BMC Geriatr
Ulutas Deniz E, Ceylan C.
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source