Results 91 to 100 of about 15,511 (292)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Medication Reconciliation in the Elderly
, 2018 Medication therapy is the most prevalent and critical intervention of health delivery and the source of most errors in healthcare. Medication errors and associated adverse drug events (ADE) have serious health and economic ramifications, and in elderly ...
Litell, Munjanja Yvonne
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INNOVATIONS in Pharmacy, 2010 Objectives: To develop and deliver an effective pharmacist-led educational initiative to clinic staff to advance medication reconciliation in the electronic medical record of an outpatient internal medicine clinic.
Sarah M. Westberg, Kathrine Beeksma
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Improving electronic medication reconciliation
, 2011 Medication reconciliation is defined by the American Society of Health- System Pharmacists (ASHP) and the American Pharmacists Association (AphA) as “the comprehensive evaluation of a patient’s medication regimen any time there is a change in therapy in ...
Filiz, Esen
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Best Practice Medication Reconciliation in the Outpatient Setting
, 2018 Background: Medication safety is a focus of the Joint Commission’s National Patient Safety Goals and research supports improved medication reconciliation as a strategy to reduce medication errors and adverse drug events.
Hession, Meghan J
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Implementation of a Post-Fall Medication Reconciliation Assessment Tool
, 2023 Older adult patients are often prescribed potentially inappropriate medications (PIMs) in the acute care hospital setting. Reducing falls in older adults requires a multi-faceted approach, including thoughtful consideration of medication regimens in this
Mosakowski, Joshua +1 more
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Clinical practice of medication reconciliation services in glaucoma patients
Yanke Xuebao[Objective:] To introduce medication reconciliation (MR) services for glaucoma patients, with the aim of delivering safe, effective, and cost-effective pharmaceutical care.
CHEN Xin, HUANG Ying
doaj +1 more source