Results 111 to 120 of about 12,613,921 (288)

Pharmacists and medication reconciliation: a review of recent literature

open access: yes, 2019
Eesha Patel,1 Joshua M Pevnick,2,3 Korey A Kennelty11Department of Pharmacy and Practice, Division of Health Services Research, University of Iowa, Iowa City, IA, USA; 2Department of Medicine, Division of General Internal Medicine, Cedars-Sinai Medical ...
Pevnick JM, Patel E, Kennelty KA
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

On the Economics of Rational Self-Medication [PDF]

open access: yes
It has been established in the medical literature that self-medicating with imperfect information about either the use of a genuine or counterfeit drug or based on wrong self-diagnosis of ailment, which is predominant especially in developing countries ...
Wisdom Akpalu
core  

Developing Quality Indicators for the Pharmacological Management of Chronic Non-Cancer Pain in Older Adult Inpatients: A RAND/UCLA Delphi Study

open access: yesJournal of Pain Research
Aljoscha Noël Goetschi,1,2 Nicole Schönenberger,1,2 Ursina Wernli,1,2 Carla Meyer-Massetti1,3 1Clinical Pharmacology and Toxicology, Department of General Internal Medicine, Bern University Hospital, Bern, Bern, Switzerland; 2Graduate School for Health ...
Goetschi AN   +3 more
doaj  

Influence of Potentially Inappropriate Medication Use on Older Australians’ Admission to Emergency Department Short Stay

open access: yesGeriatrics
Older people in the emergency department (ED) often pose complex medical challenges, with a significant prevalence of polypharmacy and potentially inappropriate medicines (PIMs) in Australia. A retrospective analysis of 200 consecutive patients aged over
Hoa T. M. Tran   +5 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Reduced prevalence of drug-related problems in psychiatric inpatients after implementation of a pharmacist-supported computerized physician order entry system - a retrospective cohort study

open access: yesFrontiers in Psychiatry
IntroductionIn 2021, a computerized physician order entry (CPOE) system with an integrated clinical decision support system (CDSS) was implemented at a tertiary care center for the treatment of mental health conditions in Lübeck, Germany.
Katharina Wien   +5 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Impact of a Multidisciplinary Approach to Polypharmacy Management in Community‐Dwelling Older Adults: Insights From a Specialized Outpatient Clinic

open access: yesAging Medicine
Objectives The increase in polypharmacy among older adults increases the risk of drug‐related problems, making multidisciplinary interventions essential.
Victoria Roncal‐Belzunce   +9 more
doaj   +1 more source

Implementation and impact analysis of a clinical pharmacy ambulatory: a two-year experience

open access: yesFrontiers in Pharmacology
IntroductionClinical pharmacy services contribute to safer and more effective medication use, yet remain underdeveloped in several countries, including Italy, due to limited recognition and funding.
Daniele Mengato   +12 more
doaj   +1 more source

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