Results 101 to 110 of about 924,741 (263)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reviewing the Record: Medical Record Reviews for Medical Toxicology Research [PDF]

Journal of Medical Toxicology, 2018
Jaiva, Larsen, Mark B, Mycyk, Trevonne M, Thompson   +2 more
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Developing Quality Indicators for the Pharmacological Management of Chronic Non-Cancer Pain in Older Adult Inpatients: A RAND/UCLA Delphi Study

Journal of Pain Research
Aljoscha Noël Goetschi,1,2 Nicole Schönenberger,1,2 Ursina Wernli,1,2 Carla Meyer-Massetti1,3 1Clinical Pharmacology and Toxicology, Department of General Internal Medicine, Bern University Hospital, Bern, Bern, Switzerland; 2Graduate School for Health ...
Goetschi AN, Schönenberger N, Wernli U, Meyer-Massetti C   +3 more
doaj  

Influence of Potentially Inappropriate Medication Use on Older Australians’ Admission to Emergency Department Short Stay

Geriatrics
Older people in the emergency department (ED) often pose complex medical challenges, with a significant prevalence of polypharmacy and potentially inappropriate medicines (PIMs) in Australia. A retrospective analysis of 200 consecutive patients aged over
Hoa T. M. Tran, Cristina Roman, Gary Yip, Michael Dooley, Mohammed S. Salahudeen, Biswadev Mitra   +5 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Reduced prevalence of drug-related problems in psychiatric inpatients after implementation of a pharmacist-supported computerized physician order entry system - a retrospective cohort study

Frontiers in Psychiatry
IntroductionIn 2021, a computerized physician order entry (CPOE) system with an integrated clinical decision support system (CDSS) was implemented at a tertiary care center for the treatment of mental health conditions in Lübeck, Germany.
Katharina Wien, Julia Thern, Anika Neubert, Britta-Lena Matthiessen, Stefan Borgwardt, Stefan Borgwardt   +5 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Impact of a Multidisciplinary Approach to Polypharmacy Management in Community‐Dwelling Older Adults: Insights From a Specialized Outpatient Clinic

Aging Medicine
Objectives The increase in polypharmacy among older adults increases the risk of drug‐related problems, making multidisciplinary interventions essential.
Victoria Roncal‐Belzunce, Marta Gutiérrez‐Valencia, Bernardo Abel Cedeño‐Veloz, Ramón San Miguel, Itxaso Marín‐Epelde, Arkaitz Galbete, Javier Preciado Goldaracena, María Irache Ezpeleta, Karmele Garaioa‐Aramburu, Nicolás Martínez‐Velilla   +9 more
doaj   +1 more source

Teaching interprofessional competency in graduate education and training – implementation and evaluation of a case-based, interprofessional online seminar for pharmacists and physicians specializing in general practice

GMS Journal for Medical Education
Aim: Interprofessional competencies should be taught, over and above undergraduate education, in post-graduate continuing education. For better collaboration between the fields of medicine and pharmacy in regard to the safety of drug therapy in cases of ...
Sabine Gehrke-Beck, Nicole Zimmermann, Stefan Wind, Ulrike Sonntag   +3 more
doaj   +1 more source