Results 111 to 120 of about 11,907,481 (308)
Impact of early in-hospital medication review by clinical pharmacists on health services utilization
Background Adverse drug events are a leading cause of emergency department visits and unplanned admissions, and prolong hospital stays. Medication review interventions aim to identify adverse drug events and optimize medication use.
C. Hohl +6 more
semanticscholar +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Aim. To conduct a bibliosemantic comparative analysis of the set of relevant terms, namely medication reconciliation, medication review and medication management as components of medicines optimisation practice, and to compile a Ukrainian glossary ...
Yuliya Nastyukha +4 more
doaj +1 more source
Medication review and reconciliation in older adults
J. Beuscart +5 more
semanticscholar +1 more source
Outcomes of a pharmacist-led medication review programme for hospitalised elderly patients.
INTRODUCTION Elderly patients are at risk of drug-related problems. This study aimed to determine whether a pharmacist-led medication review programme could reduce inappropriate medications and hospital readmissions among geriatric in-patients in Hong ...
G. Tam, H. Yang, T. Meyers
semanticscholar +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Elif Ertuna,1 Mehmet Zuhuri Arun,1 Seval Ay,2 Fatma Özge Kayhan Koçak,2 Bahattin Gökdemir,2 Gül İspirli2 1Department of Clinical Pharmacy, Faculty of Pharmacy, Ege University, Izmir, Turkey; 2Department of Internal Medicine ...
Ertuna E +5 more
doaj
Background“Behaviour that Challenges” is common in people living with dementia, resident in care homes and historically has been treated with anti-psychotics.
I. Maidment +13 more
semanticscholar +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source

