Results 201 to 210 of about 890,148 (262)

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Integrating design thinking and implementation science principles in delivering a medication review service in the community pharmacy setting-An implementation testing study. [PDF]

PLoS One
Mustafa M, Hatah E, Makmor-Bakry M.
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Medication review and deprescribing in different healthcare settings: a position statement from an Italian scientific consortium. [PDF]

Aging Clin Exp Res
Carollo M, Boccardi V, Crisafulli S, Conti V, Gnerre P, Miozzo S, Omodeo Salè E, Pieraccini F, Zamboni M, Marengoni A, Onder G, Trifirò G, Italian Scientific Consortium on medication review, deprescribing.   +13 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Pharmacist-led deprescribing of cardiovascular and diabetes medication within a clinical medication review: the LeMON study (Less Medicines in Older Patients in the Netherlands), a cluster randomized controlled trial. [PDF]

Int J Clin Pharm
Abou J, Elders PJM, Huijts D, van Marum R, Hugtenburg J.   +4 more
europepmc   +1 more source

Transmural collaborative care model for cardiovascular risk management and medication review in patients using antipsychotics in primary care (TACTIC): A study protocol of an incomplete stepped wedge cluster randomized trial. [PDF]

Contemp Clin Trials Commun
Jakobs KM, van den Brule-Barnhoorn KJ, van Lieshout J, Janzing JGE, Cahn W, Kievit W, Teerenstra S, van den Muijsenbergh M, Biermans MCJ, Bischoff EWMA.   +9 more
europepmc   +1 more source

RETRACTION: Identification of Recurrence‐Related MicroRNAs in Hepatocellular Carcinoma Following Liver Transplantation

Molecular Oncology, EarlyView.
RETRACTION: Z.‐B. Han, L. Zhong, M.‐J. Teng, J.‐W. Fan, H.‐M. Tang, J.‐Y. Wu, H.‐Y. Chen, Z.‐W. Wang, G.‐Q. Qiu, and Z.‐H. Peng, “Identification of Recurrence‐Related MicroRNAs in Hepatocellular Carcinoma following Liver Transplantation,” Molecular Oncology 6, no. 4 (2012): 445‐457, https://doi.org/10.1016/j.molonc.2012.04.001.
wiley   +1 more source

Comprehensive Medication Review Completion Rates and Disparities After Medicare Star Rating Measure.

JAMA Health Forum
Hung A, Wilson L, Smith VA, Pavon JM, Sloan CE, Hastings SN, Farley J, Maciejewski ML.   +7 more
europepmc   +1 more source