Results 111 to 120 of about 1,373,920 (341)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Improving medication management after a hospitalization with pharmacist home visits and electronic personal health records: an observational study

Drug, Healthcare and Patient Safety, 2014
Stephen Jon Kogut,1 Elaina Goldstein,1 Camille Charbonneau,1 Anita Jackson,1 Gail Patry2 1Department of Pharmacy Practice, College of Pharmacy, University of Rhode Island, Kingston, 2Healthcentric Advisors, Providence, RI, USA Background: Substantial ...
Kogut SJ, Goldstein E, Charbonneau C, Jackson A, Patry G   +4 more
doaj  

Investigating and Developing a Practical Domestic-Medication System of Public Health for Chinese Family. [PDF]

Int J Environ Res Public Health, 2023
Xu C, Zhang Y, Chen Y, Gong C.
europepmc   +1 more source

Comparison of a prototype for indications-based prescribing with 2 commercial prescribing systems [PDF]

, 2019
Importance: The indication (reason for use) for a medication is rarely included on prescriptions despite repeated recommendations to do so. One barrier has been the way existing electronic prescribing systems have been designed.
Abraham, Joanna, et al,, Garabedian, Pamela M   +2 more
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Improving the Efficiency of Medication Reconciliation in Two Taiwanese Hospitals by Using the Taiwan National Health Insurance PharmaCloud Medication System. [PDF]

Int J Gen Med, 2023
Huang PP, Poon SY, Chang SH, Kuo CW, Chien MW, Chen CC, Chiang SC.   +6 more
europepmc   +1 more source

Pharmacological effects of raas blockade in ischemic nephropathy [PDF]

, 2016
Background: The management of ischemic nephropathy due to atherosclerotic renal artery stenosis has become increasingly conservative in the modern era, with current guidelines recommending optimized medical therapy as the initial step.
Barbano, Biagio, Cianci, Rosario, Coppolino, Giuseppe, Di Mario, Francesca, Farrah, Tariq E., Fuiano, Giorgio, Gigante, Antonietta, Rivoli, Laura, Rosato, Edoardo   +8 more
core   +1 more source

Systems Barriers to Medication Management During Hospital to Home Transitions of Older Adults With Dementia [PDF]

, 2021
Maningbe Keita-Fakeye, Rhea Sharma, Sylvan Greyson, Quincy M. Samus, Ayşe P. Gürses, Sara C. Keller, Alicia I. Arbaje   +6 more
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Scoping Review of Computerized Physician Order Entry Systems in Reducing Medical Errors

Journal of Evidence Based Health Policy, Management & Economics, 2021
Background: Medical errors have dramatic clinical and economic consequences. Using various information technology can reduce medical errors and improve services’ quality via preventing medical errors.
Gisoo Alizadeh, Adineh Jafarzadeh, Mohammad Farough Khosravi   +2 more
doaj