Results 111 to 120 of about 554,085 (308)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Impact of Artificial Intelligence on the Future of Clinical Pharmacy and Hospital Settings

Journal of Research in Pharmacy Practice
This review aimed to comprehensively evaluate the impact of artificial intelligence (AI) on the future of clinical pharmacy practice and hospital settings.
Hadi Hamishehkar, Mehrdad Shahidi
doaj   +1 more source

What You Need to Know about Bar-Code Medication Administration [PDF]

, 2019
Medication errors are the most common type of preventable error. Bar-code medication administration (BCMA) technology was designed to reduce medication administration errors.
Kuhlmann, Martha, DNP, MSN, RN, FNP, PMHCNS-BC, APRN, McBee, Marie E, DNP, MSN, Patterson, Pam, DNP, MSN, NE-BC   +2 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Introducing Unit Dose Dispensing in a University Hospital – Effects on Medication Safety and Dispensing Time

Risk Management and Healthcare Policy
Hanne Katriina Ahtiainen,1,2 Carita Lindén-Lahti,1,2 Susanna Heininen,1 Anna-Riia Holmström,1 Lotta Schepel2,3 1Faculty of Pharmacy, University of Helsinki, Helsinki, Finland; 2HUS Pharmacy, Helsinki University Hospital, Helsinki, Finland; 3Quality and ...
Ahtiainen HK, Lindén-Lahti C, Heininen S, Holmström AR, Schepel L   +4 more
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Wild medicine - exploring medication management challenges in transition and interaction across actors and health sectors related to older adults receiving polypharmacy: a qualitative study

BMC Geriatrics
Background Adverse drug events represent the largest category of incidents health professionals report to regional authorities in Denmark and remain a significant challenge globally.
Gitte Wind, Karen-Marie Olesen, Janne Friis Andersen, Line Hillersdal   +3 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

TECHNOLOGIES INVOLVED IN THE PROMOTION OF PATIENT SAFETY IN THE MEDICATION PROCESS: AN INTEGRATIVE REVIEW

Cogitare Enfermagem, 2017
This study sought to identify technologies existing in the literature and their use in promoting patient safety in the medication process.
Jéssika Wanessa Soares Costa, Jéssica Martinelli Martins de Assis, Marjorie Dantas Medeiros Melo, Suênia Silva de Mesquita Xavier, Gabriela de Sousa Martins Melo, Isabelle Katherinne Fernandes Costa   +5 more
doaj   +1 more source