Results 181 to 190 of about 9,682,337 (287)

‘I need policymakers to listen’: a stakeholder needs assessment concerning anticipatory injectable medication systems, using a novel qualitative survey

Perera B, Bowers B.
europepmc   +1 more source

A systematic review and empiric examination of the conceptual and analytic overlap between allostatic load and multimorbidity. [PDF]

SSM Popul Health
Booker CL, Liang Y, Meadows A, Cranshaw O, Dearman A, Dilkes E, Hignell B, Malih AJ, Navyte G, Kumari M.   +9 more
europepmc   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Prescription Medication Use During Pregnancy and Postpartum in Sweden 2007 to 2022. [PDF]

Pharmacoepidemiol Drug Saf
Heinonen EW, Smew AI, Chacón SS, Nörby U, Stephansson O, Örtqvist AK, Axfors C, Karlsson P, Cesta CE.   +8 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

ADHD medication use and risk of self-harm: a multinational self-controlled case series study. [PDF]

BMJ Ment Health
Chan AYL, Beyene K, Park S, Shen CY, Yuen ASC, Wong KHTW, Au Yeung SL, Chan EW, Coghill D, Chui CSL, Cook S, Crystal S, Ip P, Lee TMC, Lau WCY, Li X, Lum TYS, Luo H, Rao N, Tomlin A, Wei L, Wing YK, Chan AHY, Lai EC, Shin JY, Man KKC, Wong ICK.   +26 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

The widening medication adherence gap. [PDF]

PLoS Med
Marcum ZA.
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

What opioid use disorder reveals about generalism, continuity, and care. [PDF]

Can Fam Physician
Albert OM, Arthur A, Beshara F.
europepmc   +1 more source