Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Patient and Provider Demand for and Readiness to Adopt Medications for Stimulant Use Disorders in Real-World Settings: Pre-Planning Toward Accelerated Implementation. [PDF]
Vroom EB +4 more
europepmc +1 more source
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Assessment of Electronic Clinical Monitoring Systems in the Pediatric Intensive Care Unit: Prospective Concordance Study. [PDF]
Pham D +5 more
europepmc +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Low-cost head-mounted camera system for medication-error detection. [PDF]
Nsumba S +5 more
europepmc +1 more source
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
An Evaluation of Clinician and Informatician Perspectives on Medication Harm Risk Prediction Tools for Use in a Tertiary Hospital Setting. [PDF]
Lam JYJ +4 more
europepmc +1 more source
Assessing the Utility of Over-The-Counter Medication to Track Influenza Season Timing in a South African Population. [PDF]
Makunyane MS +5 more
europepmc +1 more source
Digital and Biomarker-Based Monitoring for Schizophrenia-Treatment Adherence. [PDF]
Inshutiyimana S +5 more
europepmc +1 more source

