Pubvet, 2018 A esporotricose é uma micose zoonótica causada pela inoculação traumática de material carreando espécies do complexo Sporothrix schenkii. As lesões nodulares características ocorrem nos tecidos cutâneo, subcutâneo, linfático e, por vezes, se disseminam ...
Eduarda Aléxia Nunes Louzada Dias Cavalcanti +5 more
doaj +1 more source
Teoría y práctica de la medicina visigoda. Del enciclopedismo de Isidoro a la enfermería monástica
Asclepio: Revista de Historia de la Medicina y de la Ciencia, 2020 Cuando leemos la obra enciclopédica de Isidoro de Sevilla da la sensación de que la medicina clásica había llegado al mundo visigodo plena de racionalidad, como un conocimiento erudito y bien asentado.
Pablo C. Díaz
doaj +1 more source
Alterations in oxidative, inflammatory and apoptotic events in short-lived and long-lived mice testes [PDF]
, 2016 Aged testes undergo profound histological and morphological alterations leading to a reduced functionality. Here, we investigated whether variations in longevity affect the development of local inflammatory processes, the oxidative state and the ...
Bartke, Andrzej +7 more
core +2 more sources
Ibrutinib impairs the phagocytosis of rituximab-coated leukemic cells from chronic lymphocytic leukemia patients by human macrophages [PDF]
, 2015 We have read with great interest the recent article of Kohrt, H.E. et al1 showing that Ibrutinib prevented NK cell mediated cytotoxicity of antibody-coated CLL cells in vitro.
Almejún, María Belén +8 more
core +2 more sources
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Inteligencia artificial en la gestión de la medicina: avances y desafíos
Revista Venezolana de GerenciaLa inteligencia artificial ha emergido como una herramienta revolucionaria en la gestión de la medicina, prometiendo mejoras significativas en el diagnóstico, tratamiento y administración de los servicios de salud.
Miriam Janet Cervantes López +2 more
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Competencias del médico del siglo XXI. Un cambio necesario.
Revista Científica Ciencias de la Salud, 2019 La formación de profesionales de Ciencias de la Salud exige una adaptación, casi permanente, para dar respuesta a una sociedad en continua transición, máxime cuando se viven momentos sociales y económicos tan delicados como el actual que influyen ...
Jesús Morán Barrios
doaj +1 more source
Hormone deprivation alters mitochondrial function and lipid profile in the hippocampus [PDF]
, 2017 Mitochondrial dysfunction is a common hallmark in aging. In the female, reproductive senescence is characterized by loss of ovarian hormones, many of whose neuroprotective effects converge upon mitochondria.
Alvarez, Silvia +7 more
core +2 more sources
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Mujeres sin historia : del Hospital de La Canoa al Manicomio de la Castañeda
Secuencia, 2001 La construcción colosal de la época del porfiriato dio lugar a varias obras importantes: una extensa red ferroviaria y telegráfica, avances científicos, desarrollo de las artes, la justicia y la estadística.
Alberto Carvajal
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