Results 41 to 50 of about 1,862,680 (378)

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

Hepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan, André Megarbane, Aziz Chouchane, Deepak Karthik, Ramzi Temanni, Atilio Reyes Romero, Huiying Hua, Chun Pan, Xixi Chen, Murugan Subramanian, Chadi Saad, Hamdi Mbarek, Cybel Mehawej, Eliane Chouery, Sirin W. Abuaqel, Alexander Dömling, Sami Remadi, Cesar Yaghi, Pu Li, Lotfi Chouchane   +19 more
wiley   +1 more source

Relações entre espiritismo e medicina no Rio Grande do Sul moderno: a apometria

Anuario Colombiano de Historia Social y de la Cultura, 2018
Muitos trabalhos trataram das novas perspectivas sobre a história da medicina nos últimos anos e mostraram a integração de sujeitos que só agora aparecem como interlocutores, como médicos, curadores e adeptos de atividades religiosas. Este paper trata da
Beatriz Teixeira Weber, Dalvan Alberto Sabbi Lins   +1 more
doaj   +1 more source

Ações para a Retomada do Ensino da Humanização nas Escolas de Medicina

Revista Brasileira de Educação Médica, 2018
RESUMO Este artigo é baseado na dissertação do curso de Mestrado Profissional em Ensino em Saúde realizado pelo primeiro autor na Universidade José do Rosário Vellano – Unifenas e cujo título é “Ações para a retomada do ensino da humanização nas escolas ...
Edson Dell Amore Filho, R. B. Dias, A. C. D. D. Toledo   +2 more
semanticscholar   +1 more source

Desiccating stress-induced disruption of ocular surface immune tolerance drives dry eye disease [PDF]

, 2016
Dry eye is an allegedly autoimmune disorder for which the initiatingmechanisms and the targeted antigens in the ocular surface are not known,yet there is extensive evidence that a localized T helper type 1 (Th1)/Th17effector T cell response is ...
Galletti, Jeremías Gastón, Giordano, Mirta Nilda, Guzman, Mauricio, Keitelman, Irene Angélica, Sabbione, Florencia, Trevani, Analía Silvina   +5 more
core   +1 more source

Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury

Hepatology, EarlyView., 2022
CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli, Silvia Marchianò, Cristina di Giorgio, Rosalinda Roselli, Martina Bordoni, Rachele Bellini, Bianca Fiorillo, Valentina Sepe, Bruno Catalanotti, Chiara Cassiano, Maria Chiara Monti, Eleonora Distrutti, Angela Zampella, Stefano Fiorucci   +13 more
wiley   +1 more source

Standardization of molecular monitoring for chronic myeloid leukemia in Latin America using locally produced secondary cellular calibrators [PDF]

, 2016
Residual disease in chronic myeloid leukemia (CML) patients undergoing therapy with tyrosine kinase inhibitors (TKIs) is measured by assessing the quantity of transcripts of the BCR-ABL1 fusion gene in peripheral white blood cells. This analysis is based
Bianchini, Michele, Cross, N. C. P., Larripa, Irene Beatriz, Medina, M., Mordoh, Jose, Ruiz, María Sol, Tapia, I.   +6 more
core   +1 more source

Participation of epididymal cysteine-rich secretory proteins in sperm egg fusion and their potential use for male fertility regulation [PDF]

, 2007
Rat protein DE is an androgen-dependent cysteine-rich secretory protein (CRISP) synthesized by proximal epididymal regions. DE, also known as CRISP-1, is localized on the equatorial segment of acrosome-reacted spermatozoa and participates in gamete ...
Busso. Dolores, Cohen, Debora Juana, Cuasnicu, Patricia Sara, Da Ros, Vanina Gabriela, Ellerman, Diego Andrés, Goldweic, Nadia Micaela, Maldera, Julieta Antonella   +6 more
core   +1 more source

Violence risk assessment: what behavioral healthcare professionals should know

Revista de la Facultad de Medicina, 2015
Violence risk assessment refers to the attempt to predict the likelihood of future violent behavior so that behavioral healthcare professionals may put into place preventative, risk management measures.
Jay P Singh
doaj   +1 more source

Habilidade de Comunicação da Má Notícia: o Estudante de Medicina Está Preparado?

, 2017
– Competência Clínica. RESUMO Nas últimas duas décadas, ocorreram mudanças curriculares nos cursos de Medicina com o objetivo de formar profissionais humanizados e capazes de atender às demandas atuais.
Sombra Neto, L. Lopes, Silva, Vanessa Lauanna Lima, Lima, C. Costa, Moura, Hannah Torres de Melo, Gonçalves, Ana Luiza Mapurunga, Pires, A. P. Bezerra, Fernandes, V. Gondim   +13 more
semanticscholar   +1 more source

Medicina darwiniana

Acta Médica Costarricense, 2009
En 2009 se celebran 200 años del nacimiento de Charles Darwin y 150 años de la publicación de su libro El origen de las especies; es pregunta obligada por qué lo hizo a 50 años de edad, cuando aparentemente contaba con los elementos para hacerlo muchos años antes. De hecho, aunque no era inminente, existía el riesgo razonable de que se le adelantara en
openaire   +5 more sources