Results 61 to 70 of about 643,425 (295)

La Historia de la Medicina es una ciencia

, 2018
La historia de la medicina no es la narrativa de las glorias de su pasado ni el divertimento de la gente cultivada. Así se expresaba mi maestro Mirko Grmek (1924-2000), gran médico historiador de la medicina, cuando deseaba transmitir que la disciplina ...
A. C. R. Romo
semanticscholar   +1 more source

Blood DDIT4 and TRIM13 Transcript Levels Mark the Early Stages of Machado–Joseph Disease

Annals of Neurology, EarlyView.
Objective An abundance of select transcripts and proteins has been found to be dysregulated in blood samples of Machado–Joseph disease (MJD) carriers. Here, we aimed to: (1) identify blood transcriptional changes as potential biomarkers of MJD; (2) correlate levels of differentially expressed blood transcripts with MJD carriers features; and (3 ...
Ana F. Ferreira, Mafalda Raposo, Emily D. Shaw, Louisa Liu, João Vasconcelos, Teresa Kay, Conceição Bettencourt, Maria Luiza Saraiva‐Pereira, Laura Bannach Jardim, Maria do Carmo Costa, Manuela Lima   +10 more
wiley   +1 more source

Exposed weapons: A revised reconstruction of the facial anatomy and life appearance of the saber‐toothed cat Megantereon (Felidae, Machairodontinae)

The Anatomical Record, EarlyView.
Abstract Megantereon was a widespread saber‐toothed felid from the Pliocene and Pleistocene of the Old World and North America, but its rarity in the fossil record makes it complicated to restore its life appearance. Lack of complete specimens makes it necessary to combine information from fossils of different individuals to reconstruct their facial ...
Mauricio Antón, Gema Siliceo, Juan Francisco Pastor, Qigao Jiangzuo, Manuel J. Salesa   +4 more
wiley   +1 more source

Intestinal responses in pacu (Piaractus mesopotamicus) exposed to fasting and refeeding nutritional management

The Anatomical Record, EarlyView.
Abstract Fasting is a practice in the aquaculture industry that aims to reduce feed costs. This practice can affect the gastrointestinal system of fish. The intestine plays a pivotal role in the nutrition and overall health of fishes. The present study sought to evaluate the effects of fasting and refeeding on body weight, intestine somatic index (ISI),
Karine Nathiele Nogueira Farias, André Luiz do Nascimento Silva, Marco Shizuo Owatari, Sabrina Fuzer Gonçalves, Robson Andrade Rodrigues, Cristiane Meldau de Campos, Lilian Franco‐Belussi, Carlos Eurico Fernandes   +7 more
wiley   +1 more source

Metabolic Stress Expands Polyfunctional, Proinflammatory Th17 Cells in Patients With Psoriatic Arthritis for Whom There is Interleukin‐23–Independent Interleukin‐17 Production

Arthritis &Rheumatology, EarlyView.
Objective Genetic associations and blockade of the interleukin (IL)‐23/IL‐17 axis with monoclonal antibodies support a role for this pathway in patients with psoriatic arthritis (PsA). This study examines the requirement of IL‐23 for IL‐17 production and the role of the metabolic microenvironment in the expansion of Th17‐derived cells in patients with ...
Carmel B. Stober, Louise Ellis, Jane C. Goodall, Marc Veldhoen, J. S. Hill Gaston   +4 more
wiley   +1 more source

Comparative Analysis of Circulating and Synovial Immune Cells in Early Untreated Rheumatoid Arthritis and their relationship with molecular pathology and disease outcomes

Arthritis &Rheumatology, Accepted Article.
Objectives To assess the relationship of circulating and synovial immune cells with synovial molecular pathology and disease outcomes in early Rheumatoid Arthritis (RA). Methods Early (<12 months) treatment‐naïve RA patients (n=144) from the Pathobiology of Early Arthritis Cohort (PEAC) were included in this posthoc analysis.
Felice Rivellese, Elena Pontarini, Liliane Fossati‐Jimack, Rita A. Moura, Vasco C. Romão, João Eurico Fonseca, Alessandra Nerviani, Cankut Çubuk, Katriona Goldmann, Giovanni Giorli, Myles Lewis, Michele Bombardieri, Costantino Pitzalis, Pathobiology of Early Arthritis Cohort (PEAC) investigators   +13 more
wiley   +1 more source

Taula rodona sobre comunicació i història de la medicina en el XV Congrés d'Història de la Medicina Catalana [PDF]

, 2007
Tomàs Cabot, Josep
core   +1 more source

Medicina 5P (personalizada, predictiva, preventiva, participativa y poblacional): Un nuevo paradigma en salud pública y prevención

INSPILIP
A lo largo de la historia, en el ámbito sanitario se han evidenciado grandes avances científicos y tecnológicos en el diagnóstico y tratamiento de enfermedades.
Grace Navarrete Chávez
semanticscholar   +1 more source

The Georgia School Personnel Survey of school climate: Validity evidence from a sample of Portuguese teachers and support staff

British Educational Research Journal, EarlyView.
Abstract This study focuses on the adaptation of the Georgia School Personnel Survey (GSPS) to assess perceptions of school climate among Portuguese educational professionals, including teachers and support staff. Data from two samples (n1 = 1965; n2 = 2884) were analysed in the study.
Sofia Abreu Mendes, Jorge Sinval, Irene Cadime, Bruna Rodrigues, Richard Inman, Jesslynn Rocha Neves‐McCain, Tamika Patrice La Salle‐Finley   +6 more
wiley   +1 more source

Pharmacokinetic Prediction and Cytotoxicity of New Quercetin Derivatives

Chemistry &Biodiversity, EarlyView.
ABSTRACT Quercetin (QUE) possesses various pharmacological properties; however, its low bioavailability and solubility hinder its beneficial effects. Enzymatic glycosylation has been explored to improve these aspects. In the present study, we used a sucrose phosphorylase variant to catalyze the regioselective transglucosylation of QUE, predicted the ...
Michele Goulart dos Santos, Marie Demonceaux, Lucia Emanueli Schimith, Marine Goux, Claude Solleux, Ana Luiza Muccillo‐Baisch, Bruno Dutra Arbo, Corinne Andre‐Miral, Mariana Appel Hort   +8 more
wiley   +1 more source