Results 141 to 150 of about 514,251 (220)

Blood‐Based Epigenetic Signatures in Brazilian Males With Alcohol Use Disorder

open access: yesAddiction Biology, Volume 31, Issue 5, May 2026.
This study represents the first epigenome‐wide association analysis of Alcohol Use Disorder (AUD) in a genetically and culturally diverse Brazilian cohort. Genome‐wide DNA methylation profiling revealed hypomethylation in genes and pathways related to neuronal development, synaptic organization, intracellular signaling and cellular stress responses in ...
Laís da Silva Pereira‐Rufino   +15 more
wiley   +1 more source

Leucemia Linfoblástica aguda recidivada tratada com rituximab: relato de caso e revisão de literatura. [PDF]

open access: yes, 2007
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Borbinhão, Rodrigo Widholzer
core  

Brief report: Ketamine‐assisted “bridge therapy” for opioid tapering in complex cases

open access: yesThe American Journal on Addictions, Volume 35, Issue 3, Page 431-434, May 2026.
Abstract Background Opioid use disorder (OUD) presents major challenges, especially when combined with chronic pain and psychiatric comorbidities. A 25‐year‐old woman with OUD, chronic pain, and major depressive disorder underwent an 8‐week protocol of intravenous ketamine infusions (0.5 mg/kg weekly) as an adjunct to opioid tapering. Results Methadone
Mariana C. de Oliveira   +11 more
wiley   +1 more source

Tratamento da doença de meniére: relato de casos e revisão da literatura. [PDF]

open access: yes, 2005
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Locks, Rafael Búrigo
core  

A longitudinal network analysis of pain, psychological processes and psychological and sexual distress in women with endometriosis

open access: yesBritish Journal of Health Psychology, Volume 31, Issue 2, May 2026.
Abstract Objectives Previous studies in endometriosis have linked the experience and impact of pain to psychological distress and sexual dysfunction. However, little is known about how these factors interact over time or how underlying cognitive‐emotional processes contribute to their complex interconnections.
Sérgio A. Carvalho   +4 more
wiley   +1 more source

Transplante de córnea na infância [PDF]

open access: yes, 2012
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Felicissimo, Lucas Costa
core  

Alterações laringeas em pacientes com artrite reumatóide [PDF]

open access: yes, 2011
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Beirith, Sarah Cristina
core  

TNF‐α partially modulates the endothelial dysfunction during the acute phase of Trypanosoma cruzi infection

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 10, Page 2256-2272, May 2026.
Background and Purpose Whereas the effects of Trypanosoma cruzi (T. cruzi) infection are well‐characterised in the heart, its impact on the vasculature has received little attention. In this study, we investigated the effects of acute and chronic T. cruzi infection on vascular responsiveness and the underlying mechanisms.
Thales M. H. Dourado   +6 more
wiley   +1 more source

Stage‐Dependent Changes in Kynurenine Pathway Enzyme Expression Suggest Immune‐Related Involvement in Bladder Cancer Progression

open access: yesInternational Journal of Urology, Volume 33, Issue 5, May 2026.
ABSTRACT L‐tryptophan (Trp) metabolism through the L‐kynurenine (Kyn) pathway contributes to immune escape in neoplasms, including bladder cancer (BC). Indoleamine 2,3‐dioxygenase‐1 (IDO1) is a key enzyme, and its catabolites—Kyn, 3‐hydroxykynurenine (3HK), and 3‐hydroxyanthranilate (3HAA)—depend on other enzymes and play a crucial role in ...
Douglas Edgard Lemes   +7 more
wiley   +1 more source

Effectiveness of Influenza Vaccines in Italy in the 2024/2025 Season: A Nationwide, Test‐Negative Design Study Based on Surveillance Records

open access: yesInfluenza and Other Respiratory Viruses, Volume 20, Issue 5, May 2026.
ABSTRACT The 2024/2025 influenza season in Italy was characterised by cocirculation of influenza A and B viruses. Monitoring influenza vaccine effectiveness (IVE) remains essential to guide public health policy due to antigenic shifts and varying strain circulation.
Daniel Cifo   +12 more
wiley   +1 more source

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