Results 251 to 260 of about 418,483 (306)

Snapshots of Motion: A Novel Structural Intermediate Reveals Conserved Dynamics in Archaeal DNA Ligases

open access: yesProteins: Structure, Function, and Bioinformatics, Volume 94, Issue 6, Page 1245-1258, June 2026.
ABSTRACT We present the first x‐ray crystallographic structural evidence of an archaeal DNA ligase showing the AMP covalent adduct together with further cofactor hydrolysis, capturing a transient intermediary in the first step of the ligation reaction, triggered by the pyrophosphate hydrolysis.
A. X. Quintana‐Armas   +3 more
wiley   +1 more source

Sleep Medicine Education and Practice in Latin America: Current Challenges and Perspectives. [PDF]

open access: yesSleep Sci
Labra A   +8 more
europepmc   +1 more source

The Tariff Trap: Why Funding Health Programs Through Tariffs Harms Both Health and Democracy

open access: yesWorld Medical &Health Policy, Volume 18, Issue 2, June 2026.
ABSTRACT In 2025, the Trump Administration imposed significant tariffs on imports to the US as part of aggressive trade negotiations with other countries. Tariffs have important impacts on health that include increases in the prices that consumers and businesses pay for goods and potential damage to global supply chains.
Holly Jarman, Miranda Yaver
wiley   +1 more source

Acute‐Phase Interventions After Self‐Harm for Preventing Suicide and Recurrence: A Systematic Review and Meta‐Analysis

open access: yesActa Psychiatrica Scandinavica, Volume 153, Issue 6, Page 610-626, June 2026.
ABSTRACT Introduction Suicide risk is markedly elevated following presentation after self‐harm, yet the evidence base for interventions initiated in the immediate post‐presentation period has not been synthesized with specific attention to this high‐risk window. Clarifying which early interventions may reduce adverse outcomes is essential for informing
Guilherme Pimenta Roncete   +7 more
wiley   +1 more source

Mitochondrial Transplantation as a New Therapeutic Approach Against Cardiac and Renal Consequences in Male Rats With Myocardial Infarction

open access: yesActa Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aim Myocardial infarction (MI) is one of the leading causes of death worldwide. MI is associated with cardiac structural and functional alterations. Among these, cardiac fibrosis may be significantly influenced by mitochondrial dysfunction. We sought to evaluate whether the injection of functional mitochondria from healthy muscle could improve
María Cuesta‐Corral   +13 more
wiley   +1 more source

Changes in the 6th edition of the World Health Organization classification of tumours of the digestive system

open access: yesHistopathology, Volume 88, Issue 7, Page 1295-1314, June 2026.
Changes and new entities in the 6th edition WCT of the digestive system, including structural, molecular, and diagnostic updates to standardize terminology and improve clinical relevance. Epithelial tumours are organized by site; neuroendocrine, mesenchymal and haematolymphoid tumours have dedicated chapters, with refined grading, redefined ...
Mark J Arends   +48 more
wiley   +1 more source

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