Results 31 to 40 of about 12,753 (266)

Comparison of six-minute walk test in children with moderate/severe asthma with reference values for healthy children

Jornal de Pediatria, 2014
Objective: to compare physical performance and cardiorespiratory responses in the six-minute walk test (6MWT) in asthmatic children with reference values for healthy children in the same age group, and to correlate them with intervening variables ...
Lívia Barboza de Andrade, Diogo A.R.G. Silva, Taíza L.B. Salgado, José N. Figueroa, Norma Lucena-Silva, Murilo C.A. Britto   +5 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

VASCULITE CUT NEA COMO APRESENTAÇÃO INICIAL EM PACIENTE COM LEUCEMIA MIELOIDE AGUDA FLT3+: RELATO DE CASO

Hematology, Transfusion and Cell Therapy
Introdução: Erupções cutâneas em pacientes com leucemias agudas são complicações frequentes no curso clínico, geralmente relacionada a infiltração da doença (Leucemia cutis), porém em vários casos pode ser não leucêmica.
ASA Silva, LGF Lima, TR Evangelista, MFH Costa, HC Moura, MC Araujo, AQMS Aroucha, MCDM Cahu, VECB Dantas, MP César   +9 more
doaj   +1 more source

Stem Cell Differentiation Disperses Transcriptional Clusters via a Conserved Surface‐Condensate Trajectory

Advanced Science, EarlyView.
Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg, Irina Wachter, Agnieszka Pancholi, Matthias Akyel, Yomna Gohar, Priya Kumar, Ana Miguel Fernandes, Yuzhi Bao, Alica Schmidt‐Heydt, Marcel Piepers, Alicia Günthel, Marcel Sobucki, Elisa Kämmer, Süheyla Eroğlu‐Kayıkçı, Stephan Allgeier, Sylvia Erhardt, Vasily Zaburdaev, Carmelo Ferrai, Lennart Hilbert   +18 more
wiley   +1 more source

PNEUMOCISTOSE EM PACIENTE COM LINFOMA GRAY ZONE: RELATO DE CASO

Hematology, Transfusion and Cell Therapy
Introdução: Alguns casos com características morfológicas e fenotípicas sobrepostas ao Linfoma de Hodgkin clássico (LHc) foram reconhecidos, e a categoria de linfoma de células B - inclassificável - com características intermediárias entre o Linfoma ...
TR Evangelista, ASA Silva, LGF Lima, MFH Costa, MCDM Cahu, AQMS Aroucha, MP César, GSD Cortez, EMS Thorpe, VECB Dantas   +9 more
doaj   +1 more source

Risk of Inflammatory Bowel Disease Following Hospital‐Treated Infections and Modulatory Role of Host Genetics to Support a Multi‐Hit Pathogenesis Model

Advanced Science, EarlyView.
Hospital‐treated infections are linked to increased risk of inflammatory bowel disease in a large prospective cohort. This risk differs by infection burden, time since infection, and host immune‐genetic susceptibility. The findings support a multi‐hit pathogenesis model in which severe infection and inherited susceptibility jointly shape inflammatory ...
Haiming Zhuang, Lintao Dan, Xin Xiang, Xixian Ruan, Shuai Yuan, Jialu Yao, Jiawei Geng, Jonas F. Ludvigsson, Tian Fu, Candida Abreu, Laurent Peyrin‐Biroulet, Xue Li, Yi Xiao, Fernando Magro, Xiaoyan Wang, Jing Sun, Jie Chen   +16 more
wiley   +1 more source

Magnetoelectric Nanoparticles Enable Modulation of Cortical Networks by Low‐Intensity Static Magnetic Fields In Vitro

Advanced Science, EarlyView.
Neuromodulation strategies are increasingly needed to stimulate, restore, or replace altered neuronal activity in disease. Cobalt ferrite‐barium titanate (CFO–BTO) magnetoelectric nanoparticles convert low‐intensity static magnetic fields into local electrical modulation of cortical networks.
Nathalia Cancino‐Fuentes, Alejandro Suarez‐Perez, Elric Zhang, Hao Ye, Marta Bonato, Joana Covelo, Vitaly Pustovalov, Anton Guimera‐Brunet, Xavi Illa, Valentin Gantenbein, Cagatay M. Oral, Marta Parazzini, Salvador Pané, Maria V. Sanchez‐Vives   +13 more
wiley   +1 more source

TRANSPLANTE AUTÓLOGO COMO TERAPIA NA LEUCEMIA MIELOIDE AGUDA, REALMENTE UM TRATAMENTO OBSOLETO? – RELATO DE DOIS CASOS

Hematology, Transfusion and Cell Therapy, 2021
Introdução: Mesmo com os avanços recentes sobre a biologia da doença e em relação a marcadores prognósticos, por meio de técnicas laboratoriais modernas, muito pouco tem se avançado em drogas no tratamento de leucemia mieloide aguda (LMA) em adultos ...
VMA Bandeira, MP César, MCG Silva, AQMS Aroucha, MCB Correia, JO Vieira, ACC Lopes, MFH Costa   +7 more
doaj   +1 more source

Light‐Controlled Conductive Molecular Wire in an Artificial Lipid Membrane

Advanced Science, EarlyView.
A photochromic azobenzene derivative is shown to produce a unique photoelectric response when embedded in artificial lipid membranes. In its trans state, it forms conductive “molecular wires” that enhance membrane conductivity in the dark. Light‐induced cis isomerization suppresses this effect, showing that short‐chain molecules can modulate membrane ...
Ilaria Cardace, Lorenzo Dominici, Adriano Cola, Antonio Fieramosca, Vincenzo Ardizzone, Agostina Lina Capodilupo, Bruno Rizzuti, Milena De Giorgi, Dario Ballarini, Giuseppe Gigli, Daniele Sanvitto, Luisa De Marco   +11 more
wiley   +1 more source

TRISSOMIA DO 8 EM PACIENTE PORTADOR DE LEUCEMIA MIELOIDE CRÔNICA: RELATO DE CASO

Hematology, Transfusion and Cell Therapy
Introdução: A leucemia mieloide crônica (LMC) possui alteração citogenética definidora da doença, t (9;22) - Cromossomo Ph, sabe-se que novas alterações genéticas, podem conferir prognóstico adverso quando encontradas, como exemplo da trissomia do ...
ASA Silva, LGF Lima, MFH Costa, TR Evangelista, JO Vieira, MP Cesar, AQMS Aroucha, MCDM Cahu, VECB Dantas, GSD Cortez   +9 more
doaj   +1 more source