Results 141 to 150 of about 36,136 (232)

In Vitro Effects of Anaesthetic Compounds on a Panel of Solid Tumour Cell Lines—An Exploratory Study

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 18, September 2026.
ABSTRACT Anaesthetic agents are essential for surgical procedures, yet their potential role on tumour cell biology remains incompletely understood. Emerging evidence suggests that these compounds can act both as protumor and antitumor agents, influencing cellular processes such as proliferation, migration and cell death mechanisms.
Olga Grajdieru   +14 more
wiley   +1 more source

Pacientes pediátricos na clínica de cirurgia e medicina oral da FMDUL

open access: yes, 2019
Introdução: O Médico Dentista é orientado no sentido de promover a preservação das peças dentárias, no entanto, apesar do aumento significativo nos cuidados de saúde oral nas crianças e adolescentes, as extrações dentárias continuam a ser muitas vezes inevitáveis. As lesões orais nas crianças e adolescentes representam uma larga variedade e prevalência,
openaire   +1 more source

Transconjunctival Orbitotomy as Surgical Management of an Orbital Lipoma in a Dog

open access: yesVeterinary Ophthalmology, Volume 29, Issue 5, September 2026.
ABSTRACT Orbital lipomas are rare in dogs and may pose diagnostic and surgical challenges. This report describes the case of a 14‐year‐old female Border Collie presenting chronic exophthalmos caused by a retrobulbar mass. On ophthalmic examination, the animal maintained bilateral vision despite chronic exposure of the right ocular surface.
Lucas de Souza Viana   +4 more
wiley   +1 more source

Targeting Human Immunodeficiency Virus Integrase Beyond the Active Site: The Discovery and Development of Allosteric Integrase Inhibitors

open access: yesChemMedChem, Volume 21, Issue 16, 27 August 2026.
Human immunodeficiency virus (HIV) allosteric integrase inhibitors (ALLINIs) offer a vital alternative to standard therapies by targeting noncatalytic sites. By inducing aberrant integrase multimerization, they disrupt viral maturation. This review explores their medicinal chemistry evolution, detailing structural insights, structure–activity ...
Francesco Saccoliti   +10 more
wiley   +1 more source

Subgingival Microbiome in Young Adult Cigarette Smokers, E-Cigarette Users, and Non-Smokers. [PDF]

open access: yesMedicina (Kaunas)
Mociu M   +6 more
europepmc   +1 more source

Topliss‐Guided Optimization of Acetanilide‐Based Soluble Epoxide Hydrolase Inhibitors: Exploring the Pentafluorosulfanyl Group as a Potency‐Enhancing Motif

open access: yesChemMedChem, Volume 21, Issue 16, 27 August 2026.
Can an amide analog retain the high potency of the classic urea motif in soluble epoxide hydrolase inhibitors? Through a single unconventional switch, the introduction of the underexplored pentafluorosulfanyl group into an amide analog of TPPU, the authors restored high inhibitory potency.
Alba López‐Ruiz   +17 more
wiley   +1 more source

Pacientes geriátricos na clínica de medicina e cirurgia oral da FMDUL

open access: yes, 2019
Introduction: With the improvements in medicine and public oral health in the last decades the elderly population has been growing substantially. This specific age group because of its physiologic changes, morbility, polimedication and use of prosthetics is more susceptible to oral diseases.
openaire   +1 more source

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