Results 31 to 40 of about 49,690 (307)
Mechanically Programmable DNA Hydrogel Microparticles for 3D Cellular Systems
Advanced Materials, EarlyView.DNA hydrogel microparticles are designed to exhibit controllable viscoelasticity and stiffness across three orders of magnitude from 30Pa$30 \,\mathrm{Pa}$ to 6.5kPa$6.5 \,\mathrm{kPa}$. They are uptaken into fibroblast spheroids where they are actively remodeled by cellular forces depending on their mechanical properties.
Tobias Walther +9 more
wiley +1 more source
El pensamiento médico social de Ernesto Guevara: su presencia en el paradigma socio-médico cubano
Medisur, 2016 La personalidad de Ernesto Guevara es reconocida en el mundo por sus aportes a la lucha de los pueblos, su ética y sus principios revolucionarios, que han dejado sus huellas en la vida social, política, económica y cultural de las diferentes naciones del
Blanca Rosa Garcés Garcés +2 more
doaj +2 more sources
Santiago, 2019 Los éxitos de la salud pública en Cuba a partir de la década del sesenta del siglo pasado tienen un punto de apoyo en el ideal médico social que se logró construir. Fenómeno complejo desarrollado, en su génesis, bajo una aguda lucha ideológica.
Wirson Fabero-Rodríguez +1 more
doaj
Somatização em migrantes de baixa renda no Brasil Somatization in Brazil's low-income migrants
Psicologia & Sociedade, 2006 Este artigo tem por objetivo compreender o entrelaçamento da cultura com reações psicológicas de indivíduos expostos ao processo de migração e estabelecer relações entre o fenômeno da migração e adoecimento psicossomático.
Miguel Antônio de Mello Silva +1 more
doaj +1 more source
An Accessible Microfluidic Platform for the Generation of Polarized Brain Organoids
Advanced Materials Technologies, EarlyView.This study presents an accessible double‐gradient microfluidic device that enables controlled morphogen delivery and spatially polarized differentiation in brain organoids. By integrating a pump‐free design and stable fabrication method, the platform generates dorsal–ventral neuronal asymmetry, offering a reproducible and versatile approach to model ...
Daniel Pérez‐Calixto +6 more
wiley +1 more source
Social medicine in brazil: an alliance between sanitary education and popular pedagogy
Psicologia & Sociedade, 2013 This study unfolds from the analysis of a set of documents collected during my doctoral research, which investigated the management of filth and its relationship with the governing of populations during the formation and development of modern cities.
Ricardo Abussafy de Souza +1 more
doaj +1 more source
Revista Ciencias de la Salud, 2022 Introducción: en Colombia, la mayoría de los pueblos indígenas se encuentran en riesgo de extinción física y cultural. Además, existe una deficiencia de estudios relacionados con el análisis de narrativas propias sobre los asuntos que rodean la salud ...
Zulma Consuelo Urrego-Mendoza +3 more
doaj +1 more source
Advanced Science, EarlyView.The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi +13 more
wiley +1 more source
Advanced Science, EarlyView.SMAD4 is identified as a guardian of 3D genome architecture in lung squamous cell carcinoma. Loss of SMAD4 unleashes EP300 at chromatin loop anchors, strengthening enhancer–promoter looping and H3K27ac at the SOX2 locus to drive aberrant SOX2 activation and tumor cell proliferation.
Qian Tang +33 more
wiley +1 more source
Advanced Science, EarlyView.Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg +18 more
wiley +1 more source