Results 131 to 140 of about 282,673 (304)
Investigating the mechanism of antihypertensive actions of medicinal plants using some animal models
African Journal of Pharmaceutical Research and Development (AJOPRED)As the search for, and development of new drugs continues, drug companies engage in the large-scale pharmacological screening of medicinal plants. This creates the need to elucidate the mechanism of action of medicinal plants found to possess biological
Oloche Israel Adama +3 more
doaj
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
China's Competitive Threat to Latin America: An Analysis for 1990-2002 [PDF]
This paper explores China's competitive threat to Latin America in trade in manufactures. The direct threat in exports to third country markets appears small: LAC's trade structure is largely complementary to that of China.
Sanjaya Lall (QEH) and John Weiss
core
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Lichens Mentioned by Pedanios Dioscorides [PDF]
, 2012 Lichens are included in the classification system of fungi and have been used in medicine, pharmacy and industry from antiquity to present day in the treatment of various diseases.
Yavuz, Mustafa
core
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Development of an agroforestry system for chicken production [PDF]
, 2002 This report was presented at the UK Organic Research 2002 Conference. Because conventional production of chickens has gone further than any other animal production system towards complete control of the animal’s brief lives, development of effective ...
Engel, Cindy +2 more
core
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
ОПРЕДЕЛЕНИЕ ПАРАМЕТРОВ ТОКСИЧНОСТИ НОВОГО ПРОТИВОМИКРОБНОГО ПРЕПАРАТА ФЛУПЕТСАЛЬ 1 %
Ветеринарная патология, 2013 The article shows the results of experimental on determination of toxicity parameters of new antimicrobial chemotherapeutic medicinal product Flupetsal 1 % that contains Flurenizide.
doaj
Alternative strategies to prevent and control endoparasite diseases in organic sheep and goat farming systems – a review of current scientific knowledge [PDF]
, 2006 Infestation with gastro-intestinal nematodes in small ruminants can cause server economic losses and endanger animal welfare. The development of organic farming systems, the increased public awareness for drug residues in agricultural products and the ...
Rahmann, Gerold, Seip, Hannah
core