Results 211 to 220 of about 126,087 (296)

Transcriptional insights into aflatoxin B1 induced hepatotoxicity and comparative effects of medicinal herbs in pigs. [PDF]

BMC Vet Res
Nalpadan AA, Reyer H, Oster M, Trakooljul N, Ponsuksili S, Kozera W, Karpiesiuk K, Kępka-Borkowska K, Chałaśkiewicz K, Pierzchała M, Taniguchi H, Lepczyński A, Ślaska B, Asediya V, Pareek CS, Wimmers K.   +15 more
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Regulation of the veterinary profession: the authorization to practice, origins, milestones, and emerging challenges. [PDF]

Front Vet Sci
Vaarten J, De Briyne N, van Herten J, De Vliegher S.   +3 more
europepmc   +1 more source

Research Animals in Medicine.

Annals of Internal Medicine, 1976
openaire   +2 more sources

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Sideroxylon Obtusifolium (Roem. & Schult.) TD Penn: Knowledge and Potentialities. [PDF]

Plant Foods Hum Nutr
Conceição LDS, Vanare SP, Pegg RB, Otero DM.   +3 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

The in vivo revolution in CAR-T therapy medicinal products: challenges and regulatory prospects. [PDF]

Signal Transduct Target Ther
Lu J, Cui J, Dong J, Yan L, Wang X, Zhou D, Lu S, Wei W.   +7 more
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Diet-Dependent Chemical Profiling and Bioactivity of <i>Otala tingitana</i> Mucus: Antibacterial Activity, Antioxidant Capacity, and <i>In Vivo</i> Wound-Healing Effects. [PDF]

Molecules
Khayari AE, Alhudhaibi AM, Rour E, Bouymajane A, Taha TH, Rhazi Filali F, Abdallah EM, Ed-Dra A.   +7 more
europepmc   +1 more source