Results 211 to 220 of about 471,648 (295)

Phytochemical characterization and antifungal activity of medicinal plant extracts against Colletotrichum species associated with anthracnose in Thailand. [PDF]

PLoS One
Pitiwittayakul N, Niyomvong N, Wongsorn D, Kumla J, Suwannarach N.   +4 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Protective effects of medicinal plant-derived metabolites in cardiovascular disease targeting exosomal pathways. [PDF]

Front Pharmacol
Fu L, Han J, Lu R, Song A, Shen A, Xiong C, Liu Y, Gao Z.   +7 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

An Overview of Limonoids and Other Natural Products Isolated from the Medicinal Plant <i>Cipadessa baccifera</i> and Its Pharmacological Properties. [PDF]

Plants (Basel)
Bailly C.
europepmc   +1 more source

Flora et Vegetatio Sudano-Sambesica : Volume 14 - 2011 [PDF]

, 2011
Wittig, Rüdiger
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Highly contiguous genome of the medicinal plant Sarcandra glabra (Thunb.) Nakai. [PDF]

Sci Data
Hu Y, Tang M, Peng Y, Lan Z, Qiao Z, Qin F, Liang Y, Wei F, Wei X, Huang B, Guo X.   +10 more
europepmc   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Medicinal plant use in a context of coloniality: Congolese perspectives on lost and preserved healing traditions in Belgium. [PDF]

J Ethnobiol Ethnomed
De Meyer E, Derveeuw S, Sinatu Bolya C, de la Peña E, Ceuterick M.   +4 more
europepmc   +1 more source