Results 21 to 30 of about 184,516 (272)

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

FEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung, Mikhail G. Dozmorov, SuJeong Song, Theingi Aung, Min Hee Park, Patricia J. Sime, Wook‐Jin Chae   +6 more
wiley   +1 more source

Encapsulation of thyme essential oil in polymeric capsules using electrospray method [PDF]

Research Journal of Pharmacognosy, 2017
Background and objectives: Essential oils (EOs) of medicinal herbs are prone to degradation by oxidation, heating, or light. Encapsulation of EOs can protect these fragile volatile natural products from degradation.
F. Khalighi-Sigaroodi*, S. Mirzakhanlouei, R. Ghafarzadegan, R. Hajiaghaee, A. Mohammadnezhad   +4 more
doaj  

Compositions and biological effects of different populations of Cupressus to control adult wheat weevil (Tribolium castaneum Herbst) [PDF]

Journal of Medicinal Plants, 2023
Background: Chemical pesticides increasing use caused increased resistance in insects and increases the residue of pesticides in agricultural products and the environment.
Shahla Amini, Hamideh Khalaj, Maryam Ahvazi, Mohammadreza Labbafi   +3 more
doaj  

Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases

FEBS Letters, EarlyView.
The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher, Paula Armina V. Buco, Jia Q. Truong, Paul A. Ramsland, Monique F. Smeets, Carl R. Walkley, Jessica K. Holien   +6 more
wiley   +1 more source

Effect of different incoming feeds, defatting procedures and solvents on producing of standard silymarin extract

Journal of Medicinal Plants, 2018
Introduction: The medicinal plant milk thistle with the scientific name of Silybum marianum is an annual or biennial herb native to the Mediterranean regions and is found through the world.
reza hajiaghaee, shamsali rezazadeh, Reza Ghafarzadegan, Ameneh Mohamadnejad, Mehdi Tavakoli   +4 more
doaj  

Structural and mechanistic basis for the regulation of the chloroplast signal recognition particle by (p)ppGpp

FEBS Letters, EarlyView.
LHCPs are transported to the thylakoid membrane via the (cp)SRP pathway. This process involves a transit complex of (cp)SRP43, (cp)SRP54 and LHCP, which interacts with (cp)FtsY and Alb3 at the membrane. GTP hydrolysis by (cp)SRP54 and (cp)FtsY triggers complex dissociation.
Victor Zegarra, Paul Weiland, Pauline Anka Plitzko, Julia Thiery, Laura Czech, Felix Willmund, Patricia Bedrunka, Gert Bange   +7 more
wiley   +1 more source

Optimization of Thebaine Production using Adventitious Roots of Papaver bracteatum Lindle. by Alteration of Aeration Volume and Temperature in Bioreactor

Journal of Medicinal Plants, 2019
Background: Nowadays, the optimization of the culture conditions in bioreactors is considered as an approach to produce secondary metabolites such as thebaine.
N Qavami, H Naghdi Badi, A Qaderi, A Mehrafarin, F Khalighi-Sigaroodi, AR Zare Karizi   +5 more
doaj  

Phytochemical analysis and biological activities of essential oil and extract of Phlomis rigida Labill.

Journal of Medicinal Plants, 2021
Background: The genus Phlomis is a member of Lamiaceae (Labiatae) family. About 10 species of this genus, among more than 100 species, are endemic to Iran. Phlomis rigida Labill.
Fereshteh Heydari, Reza Ghafarzadegan, Mansour Mofasseri, Seyed Vahid Ghasemi, Mehrdad Kashefi, Reza Hajiaghaee, Saeed Tavakoli   +6 more
doaj  

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

FEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga, Kazuki Harada, Takuya Yamauchi, Tetsuya Kitaguchi, Masami Yokota Hirai, Mitsuharu Matsumoto, Takashi Tsuboi   +6 more
wiley   +1 more source

Isolation, Screening, and Identification of Actinomycetes with Antifungal and Enzyme Activity Assays against Colletotrichum dematium of Sarcandra glabra

Mycobiology, 2020
A serious leaf disease caused by Colletotrichum dematium was found during the cultivation of Sarcandra glabra in Jingxi, Rong’an, and Donglan Counties in Guangxi Province, which inflicted huge losses to plant productivity.
Lisha Song, Ni Jiang, Shugen Wei, Zuzai Lan, Limei Pan   +4 more
doaj   +1 more source