Results 121 to 130 of about 378,287 (308)
Advanced Science, EarlyView.Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang +14 more
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When the East Meets the West: the Future of Traditional Chinese Medicine in the 21st Century
康复学报, 2016 Traditional Chinese medicine (TCM) has a history of thousands of years, is a very valuable treasure left by our ancestors, and there are many things which are worth our in-depth mining. But in the past hundreds of years, with the Western medicine came to
Jin QIU
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Lei Li,1,* Xiao-Feng Liu,1,2,* Zhi-Fang Cui,1 Heng Zou,1 Shu-Ling Liu,1,2 Hong-Wu Wang1 1Respiratory Disease Center, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 101121, People’s Republic of China; 2Beijing University of ...
Cui ZF +5 more
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Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq
Advanced Science, EarlyView.Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su +10 more
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Cancer-related fatigue (CRF) is a painful, persistent, subjective, physical, emotional or cognitive feeling of fatigue caused by multiple factors related to cancer or cancer treatment, which does not match the amount of recent activity and seriously ...
CUI Yiyuan, YAN Yijing, WANG Ying, MENG Xiangju, ZHANG Qinglin, LIU Lixing, LI Sicong, FENG Li, The Working Group for the Clinical Practice Guideline for the Cancer-related Fatigue with Integrated Traditional Chinese and Western Medicine
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Advanced Science, EarlyView.Electroacupuncture (EA) ameliorates learning and memory function in 5×FAD mice by regulating the brain glucose metabolic network. This neuroprotective effect is closely related to enhancing neuronal energy utilization via the IGF1/IGF1R signaling pathway.
Shengxiang Liang +12 more
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Treating senile dementia with traditional Chinese medicine
, 2007 Han Yan1, Lin Li2, Xi Can Tang11State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China; 2Unilever Research China, Shanghai, ChinaAbstract: Senile dementia is a syndrome in the elderly ...
Xi Can Tang, Lin Li, Han Yan
core
Advanced Science, EarlyView.ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao +11 more
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Advanced Science, EarlyView.A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang +19 more
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