Results 151 to 160 of about 6,929,711 (291)

Thymosin Alpha‐1 Provides Direct Neuroprotection by Engaging the Orexin Receptor HCRTR1 to Suppress Neuronal Necroptosis

Advanced Science, EarlyView.
In this study, we unveil a thymus‐brain endocrine axis wherein Tα1 engages HCRTR1 to inhibit RIPK3‐mediated necroptosis. This study nominates the Tal‐HCRTR1‐RIPK3 axis as a potent and clinically translatable therapeutic target for stroke and neurodegeneration.
Xinmei Kang, Shisi Wang, Liubin Zhang, Mengyan Hu, Xiaotao Su, Yuxin Liu, Qin Qin, Haotong Yi, Liling Yuan, Wei Cai, Lei Wei, Zhengqi Lu   +11 more
wiley   +1 more source

Correction: Analysis of cognitive function trajectories and influencing factors in elderly patients with ischemic stroke: a prospective longitudinal study. [PDF]

Front Aging Neurosci
Chen X, Wei C, Zhao D, Zhou C, Wang W, Lu G.   +5 more
europepmc   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

HIV-induced neoantigen immunodeficiency: a novel mechanism of immune evasion in non-small cell lung cancer and implications for next-generation immunotherapies. [PDF]

J Transl Med
Yang D, Yang L, Yang J, Wang G.
europepmc   +1 more source

Machine Learning Research Trends in Traditional Chinese Medicine: A Bibliometric Review

Jiekee Lim,1 Jieyun Li,1 Mi Zhou,1 Xinang Xiao,1 Zhaoxia Xu1,2 1School of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China; 2Shanghai Key Laboratory of Health Identification and ...
Zhou M, Li J, Xiao X, Lim J, Xu Z
core  

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

THE EFFECT OF ELECTROACUPUNCTURE ON THE COMPENSATION OF VESTIBULAR IN GUINA PIG

针刺研究, 1985
Hu Senqi, Zhang Zhongfang, Xu Jianfen Shanghai Institute of Traditional Chinese Medicine   +2 more
doaj   +2 more sources

Efficacy of Appropriate Techniques of Traditional Chinese Medicine and Physical Therapy in Patients With Insulin-Associated Lipohypertrophy: A Systematic Review and Meta-Analysis. [PDF]

Int J Endocrinol
Jiang L, Fang H, Tao X, Wang L.
europepmc   +1 more source

TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2‐Mediated Glycolysis in Keratinocytes

Advanced Science, EarlyView.
In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Xiuhuan Jiang, Guoying Miao, Na Shen, Qingxia Han, Xiaoru Han, Zichang Qiao, Kexin Feng, Zhuo Tan, Yaguang Wang, Xiuhua Liu, Chen Wu, Zhenzhen Yan   +11 more
wiley   +1 more source

Correction: Integrative subtyping by bile acid metabolism identifies <i>CLCA1</i>/<i>UGT2A3</i>/<i>ZG16</i> as markers of immune dysfunction and poor prognosis in colorectal cancer. [PDF]

Front Oncol
Feng L, Wang M, Li X, Wu L, Gu D, Zhang B, Zheng P, Yang Q, Wang K, Mao G.   +9 more
europepmc   +1 more source