Bioprinted Constructs in the Regulatory Landscape: Current State and Future Perspectives
Bioprinting has rapidly emerged as a transformative technology in biomedical research, offering unprecedented potential to replicate complex tissues. Despite its promise, clinical translation remains limited due to regulatory hurdles. This review explores global regulatory frameworks, comparing approaches in the EU, U.S., China, and Australia, and ...
Francesca Perin +6 more
wiley +1 more source
Beyond Conventional Cooling: Advanced Micro/Nanostructures for Managing Extreme Heat Flux
This review examines the design, application, and manufacturing of biomimetic or engineered micro/nanostructures for managing high heat‐flux in multi‐level electronics by enhancing conductive, convective, phase‐changing, and radiative heat transfer mechanisms, highlighting their potential for efficient, targeted thermal management, and future prospects.
Yuankun Zhang +7 more
wiley +1 more source
Closing the defect after gastric endoscopic full-thickness resection with a novel linear-traction metal clip. [PDF]
Wang Q, Li W, Chen Y, Wu J, Zhang S.
europepmc +1 more source
The Space Within: How Architected Voids Promote Tissue Formation
This review explores the role of void spaces in tissue engineering scaffolds and examines four key methods for introducing porosity into hydrogels at different scales. It discusses sacrificial templating, microgels, phase separation, and 3D printing, highlighting principles, advantages, and limitations. It also addresses emerging strategies integrating
Anna Puiggalí‐Jou +3 more
wiley +1 more source
Comment on the Review: Clarifying Steroid-Associated Glaucoma-From Association to an Actionable Closed-Loop [Letter]. [PDF]
Xu L, Chen X, Liu G.
europepmc +1 more source
Sacrificial Biofabrication for Vascularization: Concept, Materials, Technologies, and Applications
Vasculature is indispensable for tissue viability in regenerative medicine. The sacrificial biofabrication enables precise fabrication of vascular channels by using temporary templates that are subsequently removed. This review defines the concept and delves into sacrificial materials, surrounding materials, fabrication technologies, and biomedical ...
Jiezhong Shi +7 more
wiley +1 more source
Correction: The role of panax notoginseng saponins in cerebrovascular neurological disorders: an overview of mechanisms and functions. [PDF]
Wang B +7 more
europepmc +1 more source
A rapid glass‐substrate 3D microfabrication method creates anatomically accurate carotid artery‐on‐a‐chip models from stroke patient scans in 2 h. These miniaturized devices replicate patient‐specific blood vessel geometry and flow patterns, enabling real‐time imaging of clot formation under controlled injury.
Yunduo Charles Zhao +14 more
wiley +1 more source
Network pharmacology-based analysis of the antithrombotic clinical efficacy and antithrombotic mechanism of Huoxue Jiedu prescription in the treatment of polycythemia vera with heat toxin and blood stasis syndrome. [PDF]
Yumin Z +7 more
europepmc +1 more source
Inspired by mussel proteins, YDC‐Gel‐Zn is a smart bone glue designed for osteoporotic implants. It adheres strongly to both metal implants and bone for initial fixation. In osteoporosis's inflammatory environment, it sequentially releases zinc ions and therapeutic peptides: the zinc modulates immune cells to reduce inflammation, while the peptides ...
Wentao Wang +9 more
wiley +1 more source

