Advances and Strategies in Enhancing mRNA Cancer Vaccines
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang+4 more
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Machine learning algorithms predict breast cancer incidence risk: a data-driven retrospective study based on biochemical biomarkers. [PDF]
Guo Q+5 more
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Er3⁺/Mn2⁺ co‐doped ZnS/CaZnOS heterostructures are developed for remote temperature and force/sound sensing. The material exhibits UV/NIR photoluminescence, with energy transfer influencing color. Mechanoluminescence intensity is measured against applied power. Temperature‐dependent photoluminescence enabled luminescence thermometry.
Marcin Runowski+7 more
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National and subnational burden of brain and central nervous system cancers in China and global from 1990 to 2021: results from the global burden of disease study 2021. [PDF]
Tu S+9 more
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Advances in Halide Perovskites for Photon Radiation Detectors
This work highlights recent progress in perovskite‐based photon radiation detectors, covering organic–inorganic hybrid, inorganic, lead‐free double, and vacancy‐ordered halide perovskites. Their detection performance is compared, material‐specific advantages and challenges are examined, and provides insight into current limitations and future ...
Liangling Wang+3 more
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Revealing the causal association among clonal hematopoiesis (CH), stroke and circulating inflammatory factors: A Mendelian randomization study. [PDF]
Yu H, Zhang G, Li W, Chen Y, Liu X.
europepmc +1 more source
This review highlights recent advancements in 3DP techniques that incorporate emerging multifunctional SMP materials for applications in e‐electronics, soft actuators, biomedical devices, and more. Abstract Shape memory polymers (SMP) have recently gained significant attention as multifunctional materials for flexible and wearable electronics ...
Muhammad Yasir Khalid+4 more
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Thinking about translational medicine and traditional Chinese medicine
Zhang Boli, Zhang Junhua, Hu Jingqing
doaj +1 more source
Correction: Modulation of lung CD11b<sup>+</sup> dendritic cells by acupuncture alleviates Th2 airway inflammation in allergic asthma. [PDF]
Cheng M+11 more
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This study presents a superhydrophilic 3D‐printed hollow microneedle patch for continuous interstitial fluid (ISF) extraction and on‐patch biomarker sensing. Combining projection micro‐stereolithography and chemical vapor deposition, high‐resolution microneedles with enhanced wettability are fabricated, enabling passive ISF uptake without external ...
Taher Abbasiasl+7 more
wiley +1 more source