Results 221 to 230 of about 76,525,237 (343)

Alveolar type 2 cell dysfunction is associated with bile acid alterations in experimental hepatopulmonary syndrome. [PDF]

Am J Respir Cell Mol Biol
Park HJ, Cho HJ, Chen P, Pederson WP, Liu B, Yi D, Juarez E, Lorson N, Bruner A, Xia X, Zheng Q, Kheshtchin-Kamel N, Liu T, Raevens S, Beers MF, Li F, Veldhuizen RAW, Zhou H, Ledford JG, Kawut SM, Dai Z, Fallon MB.   +21 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Osteoblastogenesis stimulation by human umbilical cord stem cell secretome during maxillary expansion. [PDF]

J Dent Sci
Nugraha AP, Hong G, Hariri F, Ardani IGAW, Pramusita A, Putranti NAR, Marhendra NRA, Fadzila NDR, Putranto AF, Luthfi M, Riawan W, Situmorang PC, Syahputra RA, Porntaveetus T, Shariff KA, Ananda N, Heriasti MD, Tanimoto K.   +17 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Short-Term Changes in Segmental Multi-Frequency Bioelectrical Impedance Measurements Following Water and Banana Intake: A Fixed-Order Within-Subject Study. [PDF]

Int J Med Sci
Čermáková E, Kunzová M, Olejníčková J, Loskot P, Forejt M.   +4 more
europepmc   +1 more source

The Miniature Swine as a Model in Experimental and Translational Medicine

Toxicologic pathology (Print), 2016
A. Stricker‐Krongrad, Catherine R. Shoemake, G. Bouchard   +2 more
semanticscholar   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Qili Qiangxin capsule as adjunctive therapy for heart failure after acute myocardial infarction: a GRADE-assessed systematic review and meta-analysis of randomised controlled trials. [PDF]

Front Pharmacol
Yu JH, Yu HY, Zhang JC, Chen ZY, Wang C, Wu YQ, Wang YF, Robinson N, Liu JP, Li YL, Liang SB.   +10 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Updates on the Translational Value of Idiopathic Pulmonary Fibrosis Models Across Species: Deeper Insights Through Comparative Pathology. [PDF]

Biomolecules
Gargiulo S, Gramanzini M, Bonente D, Barone V.   +3 more
europepmc   +1 more source