Results 91 to 100 of about 2,435,662 (303)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Teoria e prática das práticas alternativas

open access: yesRevista de Saúde Pública
São abordados, os fundamentos científicos e a ética da utilização das práticas de medicina alternativa em voga no Brasil. Ressalta-se que, em geral, o termo alternativo não é definido e que pode se referir aos princípios básicos ou aos métodos de ...
Fernando D. de Avila-Pires
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Gastrointestinal Headache; a Narrative Review

open access: yesEmergency, 2016
There are studies reporting primary headaches to be associated with gastrointestinal disorders, and some report resolution of headache following the treatment of the associated gastrointestinal disorder.
Majid T Noghani   +4 more
doaj  

Health Seeking Behavior in Northern KwaZulu-Natal [PDF]

open access: yes
We examine patterns of health seeking behaviour prior to death among 1282 individuals who lived in the Umkhanyakude District of Northern KwaZulu-Natal.
Alicia Menendez   +2 more
core   +1 more source

An assessment of use of traditional medicine in pregnacy and associated factors among black South African women delivering in Bertha Gxowa Hospital [PDF]

open access: yes, 2015
A research report submitted to the Faculty of Health Sciences, University of the Witwatersrand, Johannesburg In partial fulfilment of the requirements for the Degree of Master of Medicine in Family MedicineINTRODUCTION: Black South African women use ...
Mkize, Gugulethu Thokozani
core  

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Translation: Diagnosis and Treatment Protocol for Novel Coronavirus Pneumonia (Trial Version 7)

open access: yesInfectious Microbes & Diseases, 2020
National Health Commission, National Administration of Traditional Chinese Medicine⊠ van der Veen
doaj   +1 more source

Elements of a didactic strategy for the teaching-learning process of auriculotherapy in Stomatology

open access: yesRevista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2018
Background: auriculotherapy is part of traditional medicine, with recognized employment in the treatment of various stomatological conditions. Its incorporation into the training process of the stomatologist is defined by curricular strategies.Objective:
Sara Elena Panizo-Bruzón   +4 more
doaj  

Home - About - Disclaimer - Privacy