Results 221 to 230 of about 6,603,436 (290)

Engineered Nanotopography to Modulate Growth and Signaling of Neuronal Networks

open access: yesAdvanced Functional Materials, EarlyView.
This study examines the interaction between neurons and nanoscale topographies on engineered substrates. Neurons cultured on nanowires, nanopillars and nanoneedles exhibit enhanced neurite outgrowth, form more organized neuronal circuits, and display improved synaptic connectivity, compared to flat substrates.
Hao Nguyen Tran   +8 more
wiley   +1 more source

Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle

open access: yesAdvanced Functional Materials, EarlyView.
This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang   +18 more
wiley   +1 more source

Protocol for the ACTIVE trial: a multicentre, open-label, cluster-randomized controlled trial of a quality improvement programme for older adults with hip fracture in resource-limited hospitals in China. [PDF]

open access: yesBone Jt Open
Yang M   +134 more
europepmc   +1 more source

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