Results 31 to 40 of about 6,603,436 (290)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Traditional healers and mental health care in the South African context [PDF]

open access: yes, 2009
Includes abstract.Includes bibliographical references (leaves 164-191).A number of African countries have made attempts to officially recognize traditional healers as health care providers and South Africa is no exception.
Sorsdahl, Katherine
core   +1 more source

Equity, intercultural approaches, and access to information on traditional, complementary, and integrative medicines in the Americas

open access: yesRevista Panamericana de Salud Pública, 2021
Access to information and intercultural approaches in the field of health are essential for the elimination of inequities in health access and care. Intercultural models such as traditional, complementary, and integrative medicine (TCIM) are an important
Daniel F. Gallego-Pérez   +5 more
doaj   +1 more source

Development and validation of the Chinese Quality of Life Instrument. [PDF]

open access: yes, 2005
BACKGROUND: This paper describes the development of the Chinese Quality of Life Instrument (ChQOL) which is a self-report health status instrument. Chinese Medicine relies very much on asking subjective feelings of patients in the process of diagnosis ...
Kelvin Chan   +18 more
core   +1 more source

Understanding health literacy from a traditional Chinese medicine perspective

open access: yes, 2023
Health literacy is critical to improving individual and public health. However, indigenous perceptions of health are largely absent from Western-derived measurements, contributing to disparities in health outcomes between indigenous and non-indigenous ...
Wang, Grace Y   +8 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Operational Standard for Point-through-point Electroacupuncture Therapy of Traditional Chinese Medicine Rehabilitation Techniques

open access: yes, 2022
Point-through-point electroacupuncture therapy is a kind of acupuncture therapy method piercing through the point with the millimeter-needle. With this method, one needle acts on a certain part of the human body through multiple acupoints, and when ...
Working Group on Operational Standard for Point-through-point Electroacupuncture Therapy of Traditional Chinese Medicine Rehabilitation Techniques
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Clinical Practice Guidelines in Traditional Chinese Medicine Rehabilitation—Knee Osteoarthritis

open access: yes, 2020
Knee osteoarthritis (KOA) seriously affects the activity ability and quality of life of patients. Referring to the KOA guidelines both at home and abroad, and combining the evidence-based medicine, disease and patient status, clinical characteristics, as
Jiawen ZHAN   +8 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

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