Results 101 to 110 of about 9,984,497 (332)
Molecular Oncology, EarlyView.VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park +6 more
wiley +1 more source
Building a Controlled Vocabulary for Standardizing Precision Medicine Terms [PDF]
arXiv, 2018 Rapid advances of technology and development of research in precision medicine domain have led to the production of different types of biomedical data. Standard medical vocabularies were shown to be limited in dealing with such heterogeneous data and consequently, new controlled vocabulary for data integration and normalization has been proposed.
arxiv
Molecular Oncology, EarlyView.Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang +10 more
wiley +1 more source
Genome Medicine: the future of medicine
Genome Medicine, 2009 In the past decade, scientific discovery in medicine has progressed at an increasingly rapid rate, and genomic, post-genomic and bioinformatic approaches have played key roles in this progression. Our growing understanding of the human genome and proteome promises to revolutionize the practice of medicine in the 21st century. The last year has seen the
openaire +3 more sources
Analyses and Concerns in Precision Medicine: A Statistical Perspective [PDF]
arXivThis article explores the critical role of statistical analysis in precision medicine. It discusses how personalized healthcare is enhanced by statistical methods that interpret complex, multidimensional datasets, focusing on predictive modeling, machine learning algorithms, and data visualization techniques.
arxiv