Results 131 to 140 of about 18,660,361 (398)

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

Balancing access to ADHD medication

open access: yesBMC Medicine, 2023
B.M.C. Medicine
doaj   +1 more source

Medicine and physiology [PDF]

open access: green, 1920
G. E. Nesbitt   +7 more
openalex   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Emergency Medicine

open access: yesWorld Journal of Advanced Research and Reviews
Emergency defines the potential provision of rapid and effective Medical Nursing Care, in situations where life is threatened. Emergency medicine is defined as the branch of Medicine that operates within an organized EMS. Emergency Medicine System (EMS) is defined as the organized set of provision of immediate pre-hospital, in-hospital and inter ...
openaire   +3 more sources

Genome Medicine: the future of medicine

open access: yesGenome Medicine, 2009
In the past decade, scientific discovery in medicine has progressed at an increasingly rapid rate, and genomic, post-genomic and bioinformatic approaches have played key roles in this progression. Our growing understanding of the human genome and proteome promises to revolutionize the practice of medicine in the 21st century. The last year has seen the
openaire   +3 more sources

Cross-reactivity and sensitization profiles of cockroach and moth allergens provide new insights in cockroach-allergic patients

open access: yesWorld Allergy Organization Journal
Background: Inhalant insect allergens are widely implicated as common triggers of respiratory allergies, but little is known about cross-reactivity between cockroaches and other insect allergens.
Jiale Zhang, Doctor of Medicine (M.D.)   +5 more
doaj  

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

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