Results 161 to 170 of about 19,758,671 (409)

Recommendations of the Second Panel on Cost Effectiveness in Health and Medicine: A Reference, Not a Rule Book

open access: green, 2018
Cristina Carias   +9 more
openalex   +2 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Orthopaedic Sports Medicine Fellowship Interviews: Structure and Organization of the Interview Day [PDF]

open access: gold, 2017
Brett D. Haislup   +4 more
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

THE NEW ENGLAND JOURNAL OF MEDICINE

open access: yesThe Lancet, 1977
F. C. Hamdy   +39 more
semanticscholar   +1 more source

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