Results 201 to 210 of about 18,660,361 (398)

THE EVOLUTION OF MODERN MEDICINE. [PDF]

open access: green, 1922
Madue E. Abbort
openalex   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren   +16 more
wiley   +1 more source

Investing in traditional medicine: leveraging evidence and innovative research to strengthen the fight against malaria in Nigeria. [PDF]

open access: yesMalar J
Onukansi FO   +10 more
europepmc   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Accuracy of the "Surprise Question" in predicting 90-day mortality among hospitalized patients with decompensated cirrhosis. [PDF]

open access: yesHepatol Commun
Selesky M   +12 more
europepmc   +1 more source

Translating translational research into global health gains. [PDF]

open access: yesPLoS Medicine, 2013
PLOS Medicine Editors
doaj   +1 more source

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