Development of a Scoring System to Predict Suboptimal Peak Inspiratory Flow in Patients With Chronic Obstructive Pulmonary Disease. [PDF]
Kim SH+9 more
europepmc +1 more source
A crucial role for surgery in reaching the UN millennium development goals. [PDF]
PLoS Medicine Editors
doaj +1 more source
IV. A recipe: Or the ingredients of a medicine for the spreading mortal distemper amongst cows: lately sent over from Holland, where a like distemper raged amongst the black cattle [PDF]
openalex +1 more source
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren+16 more
wiley +1 more source
Investing in traditional medicine: leveraging evidence and innovative research to strengthen the fight against malaria in Nigeria. [PDF]
Onukansi FO+10 more
europepmc +1 more source
Best practice in systematic reviews: the importance of protocols and registration. [PDF]
PLoS Medicine Editors
doaj +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
wiley +1 more source
Accuracy of the "Surprise Question" in predicting 90-day mortality among hospitalized patients with decompensated cirrhosis. [PDF]
Selesky M+12 more
europepmc +1 more source
Translating translational research into global health gains. [PDF]
PLOS Medicine Editors
doaj +1 more source