Results 61 to 70 of about 17,265,566 (310)

Surgical and Endovascular Management of Aortic Thrombosis in COVID-19 and Vaccine-Induced Immune Thrombotic Thrombocytopenia

Vascular Health and Risk Management
Rojan Abdollahzadeh Mirali,1 Seyedh Saba Ramazannia Toloti,2 Yasamin Bigdeli,3 Asal Ebrahimi,4 Yasamin Roointanpour,2 Meghdad Ghasemi Gorji1,2,5 1Department of Vascular Surgery, Shiraz University of Medical Sciences, Shiraz, Iran; 2Student Research ...
Abdollahzadeh Mirali R, Ramazannia Toloti SS, Bigdeli Y, Ebrahimi A, Roointanpour Y, Ghasemi Gorji M   +5 more
doaj  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Assessment of Food Cravings, Food Intake, and Weight Status Among Saudi Adults in Central and Western Regions of Saudi Arabia: A Retrospective, Cross-Sectional Study

Nutrition and Dietary Supplements
Mohammed Zaid Aljulifi,1 Atheer Ayed M Alshutayli,2 Ahmed Mohammed A Kaseb,3 Faisal Mohammed Asiri,4 Renad Ibrahim Alzahrani,5 Nawaf Amer H Alharbi,5 Ghadeer Yahya Almasabi,5 Mudhawi Faisal Alsuliman,6 Mohammad Shakil Ahmad,1 Riyaz Ahmed Shaik1 ...
Aljulifi MZ, Alshutayli AAM, Kaseb AMA, Asiri FM, Alzahrani RI, Alharbi NAH, Almasabi GY, Alsuliman MF, Ahmad MS, Shaik RA   +9 more
doaj  

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

The case for better governance to mitigate against childhood obesity: the UK experience

BMC Medicine, 2023
BMC Medicine
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

The new medical model: a renewed challenge for biomedicine [PDF]

, 2017
Over the past 25 years, several new “medicines” have come screeching onto health care’s various platforms, including narrative medicine, personalized medicine, precision medicine and person-centred medicine.
Fuller, Jonathan
core   +1 more source

Precision Medicine in Internal Medicine

Annals of Internal Medicine, 2019
Medicine has long sought to match diagnostic and treatment approaches to the particular needs and risks of individual patients. The decreasing cost and increasing ease of genetic sequencing have propelled the rise of precision medicine. Precision medicine aims to use genetic and other information to provide care tailored to the individual patient, with
Krzysztof, Kiryluk, David B, Goldstein, John W, Rowe, Ali G, Gharavi, Ronald, Wapner, Wendy K, Chung   +5 more
openaire   +3 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Safeguarding mothers and newborns: the urgent need to address hepatitis during pregnancy

BMC Medicine, 2023
BMC Medicine
doaj   +1 more source