Results 91 to 100 of about 7,879,142 (348)
Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Rolig, Peng, and colleagues have shed new light on how dual blockade of PD1 and LAG3 enhances antitumor immunity. They found that response to immunotherapy with anti‐PD1 + anti‐LAG3 was associated with reprogramming of canonically suppressive CD4+ regulatory T cells to an inflammatory state.
Tullia C. Bruno, Anthony R. Cillo
wiley +1 more source
Mongolian medicine: History, development and existing problems. [PDF]
Chin Herb Med, 2022 Qu S, Bao J, Ao W, Bai L, Borjigidai A.
europepmc +1 more source
Vladan Đorđević, the life and work of a gymnast, scientist, politician, writer and the progenitor of gymnastics and the Sokol Movement in Serbia [PDF]
Fizička Kultura, 2018 Vladan Đorđević belonged to a generation of Belgrade Lyceum students, who later became influential representatives of science, society and politics. Tireless engagement in the social life of Belgrade and the Kingdom of Serbia, diligent performance of ...
Vukašinović Vladan
doaj
Molecular Oncology, EarlyView.Inhibition of protein SUMOylation has been shown to block tumorigenesis; however, the specific mechanisms by which SUMOylation controls the tumor‐initiating capacities remain elusive. Li et al. describe the role of Etv1 SUMOylation in cancer stem cells using mouse models of mammary gland tumorigenesis.
Veronika Yevdokimova, Yannick D. Benoit
wiley +1 more source
[The use of radioactive substances in medicine - history and development prospects]. [PDF]
Probl Endokrinol (Mosk), 2021 Sheremeta MS, Trukhin AA, Korchagina MO.
europepmc +1 more source
An Investigation of the Transfer of Traditional Medicines from the Northern Routes of the Persian Gulf to Shiraz in the Al-Buwayh Period [PDF]
Journal of Research on History of Medicine, 2020 The transfer of medicine through the Northern roads of the Persian Gulf to the shores and backshores of the Persian Gulf has a long history. In the history of post-Islamic Iran, al-Buwayh was the first government who facilitated the transfer of medicine ...
Fathali Bozorgmehrnejad +2 more
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Molecular Oncology, EarlyView.Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li +12 more
wiley +1 more source
Identifying prognostic targets in metastatic prostate cancer beyond AR
FEBS Open Bio, EarlyView.Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng +13 more
wiley +1 more source