Results 71 to 80 of about 2,097,001 (313)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Marcos históricos no estudo do cancro do pulmão Historic landmarks in the study of lung cancer

open access: yesRevista Portuguesa de Pneumologia, 2006
No presente trabalho evocam-se os marcos históricos no estudo do cancro do pulmão, desde as suas primeiras descrições até finais do século XX. Acompanha-se o nascer da nova entidade clínica, realçam-se as dificuldades do seu diagnóstico, o aumento ...
Renato Sotto-Mayor
doaj  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Tatar ladies in higher educational institutions of the Russian empire (late 19th – early 20th century)

open access: yesИсторическая этнология
This article provides archival information about Tatar girls who studied at Russian universities at the turn of the 19th and 20th centuries. It informs about the educational institutions they attended, admission to schools and the learning environment ...
Tamina A. Biktimirova
doaj   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

open access: yesMolecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti   +3 more
wiley   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga   +2 more
wiley   +1 more source

Artificial intelligence in healthcare and medicine: the history of key events, its significance for doctors, the level of development in different countries

open access: yesФармакоэкономика
The article is devoted to analysis of the stages of development and current directions of research and practical application of artificial intelligence (AI) in the field of healthcare and medicine based on scientific publications in PubMed/MEDLINE ...
A. I. Lamotkin   +4 more
doaj   +1 more source

An Investigation of the Transfer of Traditional Medicines from the Northern Routes of the Persian Gulf to Shiraz in the Al-Buwayh Period [PDF]

open access: yesJournal of Research on History of Medicine, 2020
The transfer of medicine through the Northern roads of the Persian Gulf to the shores and backshores of the Persian Gulf has a long history. In the history of post-Islamic Iran, al-Buwayh was the first government who facilitated the transfer of medicine ...
Fathali Bozorgmehrnejad   +2 more
doaj  

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