Results 211 to 220 of about 5,062,841 (308)

Beyond cytotoxic T cells: reprogrammed regulatory T cells help facilitate response to dual checkpoint blockade

open access: yesMolecular Oncology, EarlyView.
Rolig, Peng, and colleagues have shed new light on how dual blockade of PD1 and LAG3 enhances antitumor immunity. They found that response to immunotherapy with anti‐PD1 + anti‐LAG3 was associated with reprogramming of canonically suppressive CD4+ regulatory T cells to an inflammatory state.
Tullia C. Bruno, Anthony R. Cillo
wiley   +1 more source

Perceptions of research experience during internal medicine training: insights from a national survey. [PDF]

open access: yesAnn Med
Alhuneafat L   +5 more
europepmc   +1 more source

COPD management as a model for all chronic respiratory conditions: report of the 4th Consensus Conference in Respiratory Medicine

open access: gold, 2017
S Nardini   +7 more
openalex   +2 more sources

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

open access: yesMolecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková   +14 more
wiley   +1 more source

THE CONFERENCE OF WHO COLLABORATING CENTERS FOR EMERGENCY SITUATIONS, STOCKHOLM, SWEDEN, DECEMBER 5-7, 2017

open access: yesМедицина катастроф, 2018
Kipor G.V.   +4 more
doaj  

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

MEDICAL EVACUATION WITHIN SYSTEM OF LIQUIDATION OF MEDICAL AND SANITARY CONSEQUENCES OF CRISIS SITUATIONS

open access: yesМедицина катастроф, 2018
Baranova N.N.   +4 more
doaj  

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