Results 241 to 250 of about 26,997,198 (419)

Genomic and transcriptomic profiling expands precision cancer medicine: the WINTHER trial

open access: yesNature Network Boston, 2019
J. Rodón   +24 more
semanticscholar   +1 more source

Outcomes of Glenoid Labral Repair Using All-Suture Anchors. [PDF]

open access: yesOrthop J Sports Med
Loeb AE   +17 more
europepmc   +1 more source

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

open access: yesMolecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song   +13 more
wiley   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

Chinese herbal medicine: Fighting SARS-CoV-2 infection on all fronts

open access: yesJournal of Ethnopharmacology, 2021
Zhonglei Wang, Liyan Yang
semanticscholar   +1 more source

Are quality medicines affordable? Evidence from a large survey of medicine price and quality in Indonesia. [PDF]

open access: yesBMJ Glob Health
Maria V   +5 more
europepmc   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

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