Results 261 to 270 of about 26,876,580 (395)

Look-alike and sound-alike medicines: let us all be aware

, 2014
Sanjaya Mani Dixit
openalex   +2 more sources

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Addressing the Minority Tax by Building Diversity Capital: A Case-Based Discussion. [PDF]

MedEdPORTAL
Sánchez JP, Ellis D, Plaza V, Vélez A, Rodriguez J, Duque Lasio L, Quintero-Rivera F.   +6 more
europepmc   +1 more source

Market Access and Reimbursement Options For Orphan Durg Hospital Only Medicines In Europe – One Size Fits All?

, 2014
S. Vosgerau, Gernot Paulus, S. Plantoer
openalex   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Outcomes of Glenoid Labral Repair Using All-Suture Anchors. [PDF]

Orthop J Sports Med
Loeb AE, Moore Z, Ithurburn MP, Kidwell-Chandler AL, Atkinson A, Froom R, Mussell EA, Arceo C, Nguyen C, King E, Shepherd A, Beam J, Nodjomian J, Rothermich MA, Ryan MK, Emblom BA, Cain EL, Dugas JR.   +17 more
europepmc   +1 more source

Biomarker-guided personalised emergency medicine for all – hope for another hype?

, 2015
Philipp Schüetz, Drahomir Aujesky, Christian Müller, Beat P. Müller‐Stich   +3 more
openalex   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Disaster medicine in Swedish undergraduate medical education: analysing current programs and future integration in the six-year curriculum. [PDF]

BMC Med Educ
Olsson S, Kurland L, Taube F, Björås J, Robinson Y.   +4 more
europepmc   +1 more source

[To all high school seniors considering medical education: better chose an alternative medicine practitioner or veterinary career!]. [PDF]

, 2013
Henning Fischer
openalex