Results 51 to 60 of about 9,199,416 (314)

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Correlation and agreement between arterial and venous blood gas analysis in patients with hypotension—an emergency department-based cross-sectional study

International Journal of Emergency Medicine, 2023
Background Blood gas analysis is integral to assessing emergency department (ED) patients with acute respiratory or metabolic disease. Arterial blood gas (ABG) is the gold standard for oxygenation, ventilation, and acid–base status but is painful to ...
Hari Prasad, Nagasubramanyam Vempalli, Naman Agrawal, U. N. Ajun, Ajmal Salam, Soumya Subhra Datta, Ashutosh Singhal, Nishant Ranjan, P. P. Shabeeba Sherin, G. Sundareshan   +9 more
doaj   +1 more source

A Brief History of Quality Improvement in Health Care and Spinal Surgery. [PDF]

, 2020
While medical and technological advances continue to shape and advance health care, there has been growing emphasis on translating these advances into improvement in overall health care quality outcomes in the United States.
Harrop, James, Hines, Kevin, Knightly, John J, Mouchtouris, Nikolaos   +3 more
core   +1 more source

Role of contrast enhanced computed tomography abdomen in the evaluation of elderly patients presenting to the emergency with acute abdomen- prospective observational study

International Journal of Emergency Medicine
Background India’s elderly population is rapidly growing, with 149 million people aged 60 years and above in 2022, projected to double to 347 million by 2050.
Takshak Shankar, Nagasubramanyam Vempalli, Parvathy Sasidharan, Konda Sireesha, Salva Ameena, Amrita Paul, Parina Tejpal, Devinder Kumar Lalotra, Aditya Sushant Mahalle   +8 more
doaj   +1 more source

ACE2 protein expression in lung tissues of severe COVID-19 infection

Scientific Reports, 2022
Angiotensin-converting enzyme 2 (ACE2) is a key host protein by which severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) enters and multiplies within cells. The level of ACE2 expression in the lung is hypothesised to correlate with an increased
Atish Gheware, Animesh Ray, Deeksha Rana, Prashant Bajpai, Aruna Nambirajan, S. Arulselvi, Purva Mathur, Anjan Trikha, Sudheer Arava, Prasenjit Das, Asit Ranjan Mridha, Geetika Singh, Manish Soneja, Neeraj Nischal, Sanjeev Lalwani, Naveet Wig, Chitra Sarkar, Deepali Jain   +17 more
doaj   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

Neuro-leishmaniasis with cauda equina syndrome and cranial nerve palsy: a rare manifestation of recurrent atypical visceral leishmaniasis

BMC Infectious Diseases
Background Visceral leishmaniasis (VL) is a neglected tropical disease primarily affecting Brazil, East Africa, and India, with India accounting for 18% of the global burden. While VL typically presents with systemic symptoms like fever, weight loss, and
Karthick Kumar Vaitheeswaran, Baidhnath Kumar Gupta, Rahul Krishnan G, Manish Soneja, Naval K. Vikram, Upendra Baitha, Amandeep Singh, Naveet Wig, Mudsser Azam, Ruchi Singh, Ajay Garg, Nishikant Damle, Yamini Dharmashaktu   +12 more
doaj   +1 more source

Verification, Analytical Validation, and Clinical Validation (V3): The Foundation of Determining Fit-for-Purpose for Biometric Monitoring Technologies (BioMeTs) [PDF]

, 2020
Digital medicine is an interdisciplinary field, drawing together stakeholders with expertize in engineering, manufacturing, clinical science, data science, biostatistics, regulatory science, ethics, patient advocacy, and healthcare policy, to name a few.
Bakker, Jessie, Bent, Brinnae, Coravos, Andrea, Dowling, Ariel, Fitzer-Attas, Cheryl, Godfrey, Alan, Godino, Job, Goldsack, Jennifer, Gujar, Ninad, Ismailova, Elena, Manta, Christine, Peterson, Barry, Vandendriessche, Benjamin, Wang, Ke, Wood, William   +14 more
core   +2 more sources

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source